Jen Shared "DIT Day 1" - 192 Picmonics
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DIT Day 1
E. coli Overview
- Characteristics
- Gram-Negative
- Bacillus
- Purple Colony with Metallic Green Sheen
- Lactose-Fermenting
- Pink on MacConkey Agar
- Disease
- Diarrhea
- Lipid A Septic Shock
- P Pili Pyelonephritis and Cystitis
- K Capsule Neonatal Meningitis
- K Capsule Pneumonia
- H Antigen Flagella
2 mins
Listeria Monocytogenes Characteristics
- Characteristics
- Gram Positive
- Bacillus
- Intracellular
- Survives in Cold Temperature
- Actin Rocket
- Tumbling Motility
- Catalase-Positive
- Beta-Hemolytic
- Only Gram-Positive with Endotoxin-Like Structure
2 mins
Listeria Monocytogenes Disease
- Signs and Symptoms
- Soft Cheese
- Pregnant Women Have Flu-Like Symptoms
- Pregnant Women Have GI Symptoms
- Granulomatosis Infantiseptica
- Spontaneous Abortion
- Meningitis
- Monocytes in CSF
- Treatment
- Ampicillin
2 mins
Aminoglycosides
- Drug Names
- Gentamicin
- Neomycin for Bowel Surgery Prep
- Amikacin
- Tobramycin
- Streptomycin
- Mechanism of Action
- Bactericidal
- Inhibit Formation of Initiation Complex
- Cause Misreading of mRNA
- Require O2 for Uptake
- Resistance
- Resistance by Transferase Enzymes
- Acetylation
- Phosphorylation
- Adenylation
- Indications
- Gram-Negative Rod Infections
- Synergistic with B-Lactam Antibiotics
- Side Effects
- Nephrotoxicity Especially When Used with Cephalosporins
- Ototoxicity Especially When Used with Loop Diuretics
- Teratogen
5 mins
Aminopenicillin Mechanisms
- Indications
- Broader Spectrum
- Drug Names
- Ampicillin
- Amoxicillin
- Mechanism and Characteristics
- Beta-Lactamase Sensitive
- Combine with Clavulanic Acid
- Side Effects
- Hypersensitivity Reactions
- Ampicillin Rash
- Pseudomembranous Colitis
2 mins
Aminopenicillin Uses
- Drug Names
- Ampicillin
- Amoxicillin
- Indications
- Shigella
- Haemophilus Influenzae
- Salmonella
- Listeria
- Enterococci
- Proteus Mirabilis
- E. Coli
1 min
Haemophilus influenzae Characteristics
- Characteristics
- Gram-Negative
- Coccobacilli
- PRP Capsule in Type B
- Positive Quellung Reaction
- IgA Protease
- Chocolate Agar
- Factor V is NAD
- Factor X is Hematin
- Staph Aureus Provides Factor V
2 mins
Haemophilus Influenzae Disease
- Disease
- Pneumonia
- Cherry Red Epiglottitis
- Meningitis
- Otitis Media
- COPD Exacerbation
- Thumbprint Sign (on X-ray)
- Treatment
- Rifampin Prophylaxis
- Ceftriaxone
2 mins
Neisseria Meningitidis
- Characteristics
- Gram-Negative
- Diplococci
- Chocolate Agar
- Thayer-Martin Media
- VPN
- Oxidase-Positive
- Maltose Fermentation
- Glucose Fermentation
- Endotoxin
- Lipooligosaccharide (LOS) in Membrane
- Polysaccharide Capsule
- IgA Protease
- Disease
- Waterhouse Friderichsen Syndrome
- Adrenal Insufficiency
- Petechial Rash
- Treatments
- Ceftriaxone
- Rifampin Prophylaxis
5 mins
Fluoroquinolones Toxicities
- Diarrhea
- Skin Rash
- Headache
- Tendon Rupture in Adults
- Myalgias in Kids
- Damage to Cartilage
- Teratogen
- QT Prolongation
1 min
Rifampin
- Tuberculosis (TB)
- Blocks RNA Polymerization
- Haemophilus influenzae Type B
- Leprosy
- Meningitis
- P450 inducer
- Red-orange urine
55 secs
Streptococcus Pneumoniae Disease
- Signs and Symptoms
- Sickle Cell Anemia
- Sepsis in Patients with Splenectomy
- Rusty Sputum
- MOPS
- Meningitis
- Otitis Media
- Pneumonia
- Sinusitis
2 mins
Streptococcus Pneumoniae Characteristics
- Characteristics
- Gram-Positive
- Diplococci
- Lancet-Shaped
- Catalase-Negative
- Optochin-Sensitive
- Bile Soluble
- Alpha-Hemolytic
- Polysaccharide Capsule
- Positive Quellung Reaction
- IgA Protease
1 min
Mycobacterium Tuberculosis Characteristics
- Characteristics
- Mycolic Acid Cell Wall
- Acid-fast
- Carbolfuchsin Stain Red
- Lowenstein-Jensen Agar
- Serpentine Cord Factor
- Primary TB
- Primary TB
- Caseating Granuloma
- Ghon Focus
- Hilar Lymph Nodes
- Ghon Complex
- Reactivation TB
- Reactivation TB
- Reactivation in Apex
3 mins
Ethambutol
- Mechanism of Action
- Bacteriostatic
- Blocks Arabinosyltransferase
- Arabinosyltransferase Polymerizes Carbohydrates
- Carbohydrate Polymers Make Mycobacterium TB Cell Wall
- Side Effects
- Red/Green Color Blindness
- Reversible with Drug Discontinuation
40 secs
Isoniazid
- Indications
- Tuberculosis (TB)
- Mechanism of Action
- Requires Catalase Peroxidase
- Decreases Mycolic Acid Synthesis
- Fast vs Slow Acetylators
- Side Effects
- B6 Deficiency
- Neurotoxicity
- Hepatotoxicity
- Drug-induced Lupus
1 min
Cephalosporins Overview
- Mechanism of Action
- Beta lactam drug
- Inhibits cell wall synthesis
- Bactericidal
- Side Effects
- Hypersensitivity reactions
- Vitamin K Deficiency
- Disulfiram like reaction with Alcohol
- Increased Nephrotoxicity of Aminoglycosides
1 min
1st Generation Cephalosporin
- Drug Names
- Cefazolin
- Cephalexin
- Indications (PEcK Mnemonic)
- Proteus mirabilis
- E. coli
- Klebsiella
- Gram-Positive Cocci
1 min
2nd Generation Cephalosporin
- Drug Names
- Cefoxitin
- Cefaclor
- Cefuroxime
- Indications (PEcK HENS Mnemonic)
- Proteus mirabilis
- E. coli
- Klebsiella
- Gram-Positive Cocci
- Haemophilus influenzae
- Enterobacter
- Neisseria
- Serratia marcescens
2 mins
3rd Generation Cephalosporin
- Drug Names
- Cefotaxime
- Ceftriaxone
- Cefdinir
- Ceftazidime
- Pseudomonas
- Indications
- Serious Gram-Negative Bacteria Resistant to Other Beta-Lactams
1 min
