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General Physiology - Excitable Cells Active Properties
Mechanism of Action
Blocks Voltage-Gated Na+ Channels
Neuron Resting Potential
More Na+ Outside
K+ Leaks Out
More K+ Inside
Voltage-Gated Sodium Channels are Closed
Neuron Action Potential Initiation
Summation of Signals
-50 mV Threshold Value Reached
Voltage-Gated Sodium Channels Open
Potassium Channels open
Neuron Action Potential Propagation
Absolute Refractory Period In Preceding Na+ Channels
Neighboring Voltage Gate Channels Open
Nodes of Ranvier
Myelination Increases Propagation Speed
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