Chiara Shared "NURS 260" - 8 Picmonics
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NURS 260
- Pathophysiology
- Autosomal Dominant
- Mutation on Chromosome 5
- APC Tumor Suppressor Gene Mutation
- Overexpression of β-catenin
- Two-Hit Hypothesis
- manifestations
- Postpubertal Appearance of Thousands of Polyps
- Always Involves Rectum
- Pancolonic
- Associations
- Hepatoblastoma
- Most Patients Develop Colorectal Carcinoma (CRC) by 40 years of age
- Interventions
- Prophylactic Colectomy
- Thickened Mucus
- Recurrent Pulmonary Infections
- Pulmonary Congestion
- Pancreatic Insufficiency
- Steatorrhea
- Fat-Soluble Vitamin Deficiencies
- Salty Taste to Skin
- Meconium Ileus
- Delayed Growth and Poor Weight Gain
- Pathophysiology
- Trisomy 21
- Meiotic Nondisjunction
- Signs and Symptoms
- Intellectual Disability (Mental Retardation)
- Single palmar crease
- Flat Facies
- Duodenal Atresia
- Hirschsprung's Disease
- Septum Primum Type ASD
- Endocardial Cushion Defects
- Prominent Epicanthal Folds
- Increased Risk of Acute Lymphoblastic Leukemia
- Alzheimer's Disease
- Autosomal Dominant
- Absent or Defective LDL Receptor
- Increases LDL
- Accelerated atherosclerosis
- Tendon Xanthomas
- Corneal Arcus
- Familial Adenomatous Polyposis
- Autosomal Dominant
- Mutation of APC gene
- Chromosome 5q
- 2 hit hypothesis
- Thousands of polyps arise starting after puberty
- Pancolonic; always involves the rectum
- Colonoscopies starting at age 10 and repeated every year
- Prophylactic colectomy or 100% progress to Colorectal Cancer
- Assessment
- Decreased GABA
- Appears around Age 40
- Slow Cognitive Decline
- Choreiform Movements
- Non Repetitive Jerks
- Interventions
- Neuroleptics
- Tetrabenazine
- Genetic Counseling
- Considerations
- Stages of Disease
- High Calorie Diet
- Characteristics
- Non-enveloped
- Circular
- Double Stranded DNA
- Disease
- Warts 1, 2, 6, 11
- Condyloma acuminata
- Type 16, 18
- Cervical Carcinoma
- Penile Carcinoma
- AIDS/Immunocompromised
- Worsened by Smoking
- Diagnosis
- Koilocytic change in squamous epithelium
- Pyknotic Nuclei Surrounded by Clear Halo
- Treatment
- Vaccine Available
- CAUTION
- Change in Bowel or Bladder Habits
- A Sore That Does Not Heal
- Unusual Bleeding or Discharge
- Thickening or Lump in the Breast or Elsewhere
- Dyspepsia (Indigestion)
- Obvious Change to Warts or Moles
- Nagging Cough
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