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Bicarbonate Reabsorption from the Kidney Increases pH
Kidney Excretion of H+ Increases pH
Alveolar Gas Equation
Partial Pressure of Alveolar Oxygen (PAO2)
Partial Pressure of Oxygen in the Inspired Air (PIO2)
PIO2 Normally Approximated = 150 mmHg
Arterial Partial Pressure of CO2 (PaCO2)
Respiratory Quotient (R)
R Normally Approximated = 0.8
PAO2 = PIO2 - (PaCO2/R)
Increased PaCO2 > 45
Barbiturates Depress Central Respiratory Center of Brain
Opioids Depress Central Respiratory Center of the Brain
Respiratory Muscle Weakness/Paralysis
Respiratory Acidosis Interventions
Restrictive Lung Disease
Respiratory Alkalosis Interventions
Treat Underlying Cause
Mechanically Ventilated Patients
Decrease Tidal Volume and/or Respiratory Rate
Give Adequate Pain Control and Sedation
Rebreathing into Paper Bag
Compensatory Drop in Serum Bicarbonate
Correct CO2 Slowly
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