Hannah Shared "NeuroExam2Drugs" - 11 Picmonics

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NeuroExam2Drugs

Levodopa/Carbidopa (Sinemet)
Indications
Parkinson's Disease
Mechanism of Action
Increase Dopamine in Brain
Cross blood-brain barrier
Increase bioavailability
Side Effects
Arrhythmias
Dyskinesia
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1 min
Entacapone
Mechanism of Action
Inhibits COMT
Use
Parkinson's Drugs
Side Effects
Similar to those of carbidopa-levodopa
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Tolcapone
Mechanism of Action
COMT inhibitor
Side Effects
Sim to carbadopa-levodopa
Liver Failure
Use
Parkinson's Disease
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Benztropine (Cogentin)
Mechanism
Anticholinergic
Indications
Parkinson's Disease
Acute Dystonia
Side Effects
Blurred Vision
Dry Mouth
Urinary Retention
Tachycardia
Constipation
Psychosis
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2 mins
Methylpredisolone
Drug Type
Glucocorticoid
Use
Multiple Sclerosis
Mechanism of Action
Binds to cytoplasmic receptors
Side Effects
Insomnia
Elevated blood sugar
Infections
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Dimethyl fumarate
Use
Relapsing Remitting Multiple Sclerosis
Mechanism of Action
Activates Nrf2 pathway
Administration
Oral
Side Effects
Skin Flushing
GI problems
Infections
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Fingolimod
Use
Administration
Relapsing remitting MS
Oral
Mechanism of Action
Antagonist of sphingosine-1-P type 1 receptor
Traps T and B cells
Side Effects
Infections
Skin cancer
Macular edema
Bradycardia & hypotension
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Interferon beta 1a and 1b
Use
Multiple sclerosis
Mechanism of Action
Suppress T cell activation & proliferation
Administration
Subcutaneous Injection
Intramuscular injection
Side Effects
Skin Reactions at Injection Site
Influenza-like syndrome
Hepatotoxicity**
Neuropsychiatric symptoms
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Glatiramer
Use
Relapsing Multiple Sclerosis
Administration
Subcutaneous Injection
Mechanism
Binds to MHC II
Side Effects
Skin Reactions at Injection Site
Myocardial Infarction Mimic
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Natalizumab
Use
Multiple Sclerosis
Mechanism of Action
Reduce lymphocyte counts
Side Effects
Cardiotoxic
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Teriflunomide
Use
Relapsing Remitting MS
Mechanism of Action
Decreased lymphocytes
Side Effects
GI problems
Hepatotoxicity
Teratogenic
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