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Alexis Shared "Pharm module 1" - 7 Picmonics

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Pharm module 1

P450 Inducer
Griseofulvin
Phenytoin
Carbamazepine
Rifampin
Barbiturates
Chronic Alcohol Use
St. John's Wort
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51 secs
Peak and Trough
Peak
Highest Concentration
Trough
Lowest Level of Therapeutic Range
Obtain Before Next Dose
Half-Life
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2 mins
Alpha 1 Receptor
Characteristics
Gq Subunit
Increase Vascular Smooth Muscle Contraction
Increase Pupillary Dilator Muscle Contraction
Increase Intestinal and Bladder Sphincter Muscle Contraction
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1 min
Alpha 2 Receptor
Characteristics
Gi Subunit
Decrease Sympathetic Outflow
Decrease Insulin Release
Decrease Lipolysis
Increase Platelet Aggregation
Decrease Aqueous Humor Production
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2 mins
Beta-1 Receptor
Characteristics
Gs Protein Class
Increased Heart Rate
Increased Contractility
Increase Renin Release
Increased Lipolysis
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44 secs
Beta-2 Receptor
Characteristics
Gs Protein Class
Cardiopulmonary
Increased Heart Rate
Increased Contractility
Bronchodilation
Metabolic
Increased Lipolysis
Increased Insulin
Increased Glycogenolysis
Increased Cellular Potassium Uptake
Considerations
Increased Aqueous Humor Production
Vasodilation
Decrease Uterine Tone
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2 mins
P450 Inhibitors
Quinidine
Ciprofloxacin
Isoniazid
Grapefruit Juice
Acute Alcohol Use
Erythromycin (Macrolide)
Indinavir
Cimetidine
Sulfonamides
Ketoconazole
Amiodarone
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2 mins

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