Hope Shared "HHD-2 Pharm" - 43 Picmonics
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HHD-2 Pharm
Plasmodium General
- Characteristics
- Protozoa
- Malaria
- Anopheles Mosquito
- Signs and Symptoms
- Cyclic Fever
- Headache
- Anemia
- Splenomegaly
- Diagnosis
- Blood Smear
- Treatment
- Chloroquine
- Mefloquine for Resistant Types
3 mins
G6PD Deficiency
- X-linked Recessive
- Hemolytic Anemia
- Inflammatory Response
- Fava Beans
- Sulfonamides
- Primaquine
- Anti TB Drugs
- Heinz Bodies
- Bite Cells
- Prevalent Among African Americans due to Increased Malarial Resistance
2 mins
Metronidazole
- Mechanism of Action
- Bactericidal
- Forms Free Radical Toxic Metabolites
- Damages DNA
- Indications
- Giardia lamblia
- Entamoeba Histolytica
- Trichomonas
- Gardnerella
- Anaerobes
- Side Effects
- Metallic taste
- Disulfiram like Reaction with Alcohol
2 mins
Amphotericin B
- Indications
- Systemic Mycosis
- Fungal Meningitis
- Last Resort for Protozoan infections
- Mechanism
- Polyene
- Binds Ergosterol
- Forms Membrane Pores
1 min
Amphotericin B Side Effects & Toxicity
- Side Effects
- Fever/Chills "Shake and Bake"
- Nephrotoxicity
- Milder with Liposomes
- Hypotension
- Anemia
- IV Phlebitis
- Arrhythmias
1 min
Flucytosine
- Indications
- Cryptococcus
- Candida
- Used in Combination with Amphotericin B or Azoles
- Mechanism
- Inhibits DNA and RNA Synthesis
- Converted to 5-FU by Cytosine Deaminase
- Side Effects
- Bone Marrow Suppression
1 min
Terbinafine
- Indications
- Dermatophytosis
- Onychomycosis
- Mechanism
- Inhibits Squalene Epoxidase
- Side Effects
- Hepatotoxicity
- GI Distress
- Taste Disturbances
- Headache
2 mins
Griseofulvin
- Mechanism
- Disrupts Microtubules in Mitosis
- Indications
- Antifungal for Superficial Infections
- Tinea and Ringworm
- Side Effects
- Teratogen
- P450 Inducer
- Confusion
- Headache
2 mins
Nystatin
- Indications
- Candidiasis
- Vaginal
- Oral
- Cutaneous
- Mechanism
- Polyene
- Binds Ergosterol
- Forms Membrane Pores
- Topical form of Amphotericin B
- Side Effects
- Rash
1 min
Cimetidine and Famotidine (H2 Receptor Blockers)
- -tidine Suffix
- Mechanism
- H2 Receptor Blocker
- Indications
- Suppress Gastric Acid Secretion
- Side Effects (All)
- Pneumonia
- Side Effects - Cimetidine
- Anti-androgen Effects
- CNS Changes
2 mins
Proton Pump Inhibitors (PPIs)
- "-prazole" Suffix
- Indications
- Zollinger-Ellison Syndrome
- Gastritis
- Peptic Ulcer
- Gastroesophageal Reflux Disease (GERD)
- Mechanism
- Inhibit H+/K+/ATPase
- Side Effects
- Hip fracture
- Pneumonia
2 mins
Dinoprostone and Misoprostol
- Mechanism
- Prostaglandins
- Indications
- Promote Cervical Ripening
- Prevent GI Ulcers
- Medical Abortion
- Side Effects
- Fetal Distress
- Hyperstimulation of Uterus
- Considerations
- Vaginal Insertion
- Give Before Induction of Labor
2 mins
Metoclopramide
- Indications
- Antiemetic
- Promotility Agent
- Mechanism
- Increased Resting Tone
- Antagonist at D2 Receptor
- Side Effects
- Parkinsonian Symptoms
- Galactorrhea
- Contraindication
- Small Bowel Obstruction
- Parkinson's Disease
2 mins
Irritable Bowel Syndrome (IBS) Interventions
- Interventions
- Identify Triggers
- Increase Fiber Intake
- Probiotics
- Anticholinergics
- Tricyclic Antidepressants (TCAs)
- Loperamide
- Linaclotide
- Medications for Women
- Tegaserod (Zelnorm)
- Lubiprostone (Amitiza)
- Alosetron (Lotronex)
2 mins
Ondansetron
- Indications
- Postoperative Vomiting
- Chemotherapy-induced Nausea and Vomiting
- Mechanism
- 5-HT3 Serotonergic Antagonist
- Centrally-acting Antiemetic
- Side Effects
- Headache
- Constipation
- QT Prolongation
1 min
Zanamivir (Relenza) and Oseltamivir (Tamiflu)
- Indications
- Influenza A and B
- Treatment and Prophylaxis
- Mechanism
- Inhibits Release of New Virus
- Inhibits Influenza Neuraminidase
1 min
Foscarnet
- Indications
- CMV Retinitis
- Acyclovir-resistant HSV
- Mechanism
- Does Not Require Activation (by Viral Kinase)
- Inhibits Viral DNA Polymerase
- Pyrophosphate Analog
- Resistance through Mutated DNA Polymerase
- Side Effects
- Nephrotoxicity
- Electrolyte Abnormalities
- Hypokalemia
- Hypocalcemia
- Hypomagnesemia
2 mins
Acyclovir (Zovirax)
- Mechanism
- Guanosine Analog
- Inhibits Viral Replication
- Thymidine Kinase Activation
- Indications
- Herpes Simplex Virus (HSV)
- Varicella Zoster Virus (VZV)
- Side Effects (Oral)
- Headache
- GI Distress
- Side Effects (IV)
- CNS Toxicity
- Nephrotoxicity (Crystalline Nephropathy)
- Considerations
- Prevents Recurrent Episodes
- Slow IV Infusion
2 mins
Ganciclovir
- Indications
- Cytomegalovirus (CMV)
- Immunocompromised
- Mechanism
- Guanosine Analog
- Disrupts DNA Synthesis
- Inhibits Viral DNA Polymerase
- Side Effects
- Hematologic Effects
- Nephrotoxicity
1 min
Ribavirin
- Mechanism
- Hypermutation in RNA Viruses
- Inhibits Inosine Monophosphate Dehydrogenase
- Indications
- Hepatitis C
- Viral Hemorrhagic Fevers
- Respiratory Syncytial Virus (RSV)
- Side Effects
- Hemolytic Anemia
- Teratogen
1 min
