Suzanne Shared "Pharm 1 Week 4" - 42 Picmonics
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Pharm 1 Week 4
Erythropoietin
- Mechanism
- Stimulates RBC Production
- Indications
- Chronic Renal Failure
- Anemia
- Side Effects
- Increased Risk of Thrombosis
- Pelvic and Limb Pain
- Hypertension
- Considerations
- Do Not Shake
- Monitor Hemoglobin (Hgb) Weekly
- May Accelerate Tumor Progression
2 mins
Cobalamin (Vitamin B12)
- Mechanism
- Vitamin B12
- Indications
- Vitamin Deficiency
- Pernicious Anemia
- Side Effects
- Hypokalemia
- Arthralgia
- Dizziness
- Considerations
- IM Injection for Pernicious Anemia
- Never Give IV
2 mins
Iron (Ferrous Sulfate)
- Mechanism
- Ferrous Salts
- Indications
- Anemia
- Side Effects
- GI Distress
- Nausea and Vomiting
- Dark Stools
- Considerations
- Take Between Meals
- Liquid can Stain Teeth
- Keep out of Reach from Children
- Caution with GI Disorders
- Avoid Antacids
3 mins
Stomach Digestion
- Characteristics
- Chief Cells Secrete Pepsinogen
- Pepsinogen Turned to Pepsin By H+
- Protein Breakdown Begins
- Mucous Cells Secrete Mucus and Bicarbonate
- G Cells Secrete Gastrin
- Gastrin Stimulates Parietal Cell HCl Release
- Parietal Cells Secrete Intrinsic Factor
2 mins
Peptic Ulcer Disease Interventions
- Combination Drug Therapy
- Two Antibiotics
- Proton Pump Inhibitor (PPI)
- Decrease Acid Secretion
- Avoid NSAIDs
- Diet and Lifestyle Changes
1 min
Proton Pump Inhibitors (PPIs)
- "-prazole" Suffix
- Indications
- Zollinger-Ellison Syndrome
- Gastritis
- Peptic Ulcer
- Gastroesophageal Reflux Disease (GERD)
- Mechanism
- Inhibit H+/K+/ATPase
- Side Effects
- Hip fracture
- Pneumonia
2 mins
Omeprazole (Prilosec)
- "-prazole" Suffix
- Indications
- Zollinger-Ellison Syndrome
- Gastritis
- Peptic Ulcer
- Gastroesophageal Reflux Disease (GERD)
- Mechanism
- Proton Pump Inhibitor (PPI)
- Inhibit H+/K+/ATPase
- Side Effects
- Hip Fracture
- Pneumonia
2 mins
Cimetidine and Famotidine (H2 Receptor Blockers)
- -tidine Suffix
- Mechanism
- H2 Receptor Blocker
- Indications
- Suppress Gastric Acid Secretion
- Side Effects (All)
- Pneumonia
- Side Effects - Cimetidine
- Anti-androgen Effects
- CNS Changes
2 mins
Ondansetron
- Indications
- Postoperative Vomiting
- Chemotherapy-induced Nausea and Vomiting
- Mechanism
- 5-HT3 Serotonergic Antagonist
- Centrally-acting Antiemetic
- Side Effects
- Headache
- Constipation
- QT Prolongation
1 min
Promethazine (Phenergan)
- Mechanism
- Histamine H1 Receptor Antagonist
- Weak Dopamine Antagonist
- Indications
- Nausea and Vomiting
- Motion Sickness
- Side Effects
- Respiratory Depression
- Sedation
- Anticholinergic Effects
- Extrapyramidal Symptoms
- Considerations
- Use Large Bore IV
- Monitor for Tissue Necrosis
2 mins
Pancreatin, Pancrelipase (Pancreatic Enzymes)
- Mechanism
- Pancreatic Enzymes
- Indications
- Cystic Fibrosis
- Pancreatic Insufficiency
- Side Effects
- GI Distress
- Considerations
- Inactivated by Gastric Acid
- 24 Hour Fat Excretion
- Take with Every Meal and Snack
2 mins
Osmotic Laxatives
- Mechanism of Action
- Increases Osmotic Load
- Indications
- Hepatic Encephalopathy
- Constipation
- Drugs
- Magnesium Hydroxide
- Magnesium Citrate
- Polyethylene Glycol
- Sorbitol
- Lactulose
- Side Effects
- Diarrhea
- Dehydration
- Considerations
- Misused in Bulimia Nervosa
2 mins
Antibiotics Overview
- Cell Wall Inhibitors
- Cell Wall Inhibitors
- Penicillins
- Cephalosporins
- Monobactams
- Glycopeptides
- Carbapenems (Imipenem & Meropenem)
- Beta-Lactamase Inhibitors
- Protein Synthesis Inhibitors
- Protein Synthesis Inhibitors
- Aminoglycosides
- Macrolides
- Clindamycin
- Tetracyclines
- Linezolid
- Chloramphenicol
- Other
- Fluoroquinolones
- Sulfonamides
4 mins
Penicillin
- Mechanism of Action
- Weakens Cell Wall
- Indications
- Gram-Positive Infections
- Prophylaxis
- Side Effects
- Pain at IM Injection Site
- Allergic Reaction
- Considerations
- Skin Tests
- Allergy ID
- Medication Education
2 mins
Ampicillin and Amoxicillin
- Mechanism
- Aminopenicillin
- Indications
- Broad Spectrum Penicillin
- Gram-Positive and Some Gram-Negative Infections
- Side Effects
- Rash
- Ampicillin Rash in EBV
- Diarrhea
- Pseudomembranous Colitis
- Allergic Reaction
- Considerations
- No Effect Against Staph Aureus
- Often Combined with Beta-Lactamase Inhibitor
2 mins
Cephalosporins
- Starts with "Cef-"
- Mechanism of Action
- Bactericidal
- Indications
- Gram-Positive and Gram-Negative Infections
- Side Effects
- Allergic Reactions
- Thrombophlebitis
- Bleeding
- Contraindications
- Renal Impairment
- Considerations
- Avoid IV Calcium with Ceftriaxone
- No Alcohol
2 mins
Macrolides
- End in "-thromycin"
- Mechanism of Action
- Bacteriostatic
- Indications
- Alternative for Penicillin Allergy
- Respiratory Infections
- Pneumonia
- Side Effects
- QT Prolongation and Sudden Death
- C.Diff Overgrowth
- GI Distress
- Considerations
- Slow IV Infusion
2 mins
Macrolides Side Effects
- Side Effects
- Diarrhea
- Prolonged QT Interval
- P450 Inhibitor
- Cholestatic Hepatitis
- Skin Rash
- Eosinophilia
3 mins
Aminoglycoside Overview
- End in "-mycin"
- GNATS
- Gentamicin
- Neomycin
- Amikacin
- Tobramycin
- Streptomycin
- Mechanism of Action
- Bactericidal
- Requires Oxygen for Uptake
- Synergistic with β-lactam Antibiotics
- Indications
- Severe Gram-Negative Infections
- Bowel Surgery Prep
- MECHANISM OF RESISTANCE
- Bacterial Transferases
3 mins
Aminoglycoside Side Effects
- Side Effects
- Ototoxicity
- Nephrotoxicity
- Respiratory Paralysis
- Contraindications
- Pregnancy
- Considerations
- Peak and Trough
- Never Mix with Penicillin in Same IV
2 mins
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