Aaron Shared "Pharm I" - 18 Picmonics

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Pharm I

GUI
Bladder
adr
Duloxetine
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Monoamine Oxidase Inhibitors; moa; use
Monoamine Oxidase Inhibitors (MAO-Is) moa
MOI se
MOI drug interactions
MOI avoid with...
Do not use in conjunction with other...
Lithium moa
Lithium use
Lithium Pharmacokinetics
Lithium se
Lithium drug interactions
Lithium monitor
Lithium toxicity
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Antidepressants-Anxiolytics
SSRI's
SSRI MOA; use; pharmacokinetics
SSRI se
SSRI Additives
monitor
monitor
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Atypical Antidepressants
Bupropion moa
Bupropion use; se; drug interactions
Bupropion C/I
Mirtazapine moa
Mirtazapine use; se
Mirtazapine Drug Interactions; monitor
Trazodone moa
Trazadone use; pharmacokinetics
Trazadone se; drug interactions
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Benzodiazepines, Buspirone, Flumazenil
Oxazepam Triazolam use
Alprazolam Lorazepam Temazepam use
Diazepam Chlordiazepoxide use
Benzo moa
Benzo se
Azapirones: Buspirone
Antidote for BZD overdose: moa
Flumazenil may...
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Merperidine-Like, Methadone-Like, Mixed Agonist-Antagonist
Merperidine use; Pharmacokinetics
Fentanyl use; pharmacokinetics
Methadone use; pharmacokinetics
Pentazocine use; se
Buprenorphine use
Butorphanol use; se
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Neuroleptics
Neuroleptics --> First Generation "Typicals" moa; use
Chloropromazine pharmaco; se
Haloperidol pharmaco; se
Neuroleptics --> First Generation "Typicals" class se
Neuroleptics --> Second Generation "Atypicals"
Clozapine moa; use
Clozapine se
Clozapine other
Risperidone moa; use
Risperidone se
Risperidone other
Quetiapine moa; use
Quetiapine se
Aripiprazole (Abilify) moa; use
Aripiprazole se
Olanzapine moa; use
Olanzapine se
Ziprasidone moa; use
Ziprasidone se
Ziprasidone other
Typical
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Serotonin Antagonists
Phenoxybenzamine
Phenoxybenzamine
5HT2A antagonist
Alpha antagonist
Used to treat hypertension
Given to Pheo patients before surgery
Ketanserin
Ketanserin
Alpha adrenergic and 5HT2A antagonist
Used to treat hypertension
Cryproheptadine
Cryproheptadine
Blocks 5HT2A-C receptors
Also blocks H1 (histamine), DA, and muscarinic ACh receptors
Use: Cold induced urticaria
Use: Carcinoid Tumor
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Serotonin Norepinephrine Reuptake Inhibitors (SNRIs)
Indications
Depression
Diabetic Peripheral Neuropathy
Duloxetine
Panic and Anxiety
Venlafaxine
Mechanism of Action
Inhibits Reuptake of Serotonin and NE
Side Effects
Hypertension
Insomnia
Nausea and Vomiting
Decreased Libido
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1 min
SNRI's)
Venlafaxine moa
Duloxetine moa
Levimilnacioran moa; use
Milnacipran moa; use
Venlafaxine se
Duloxetine se
Levimilnacioran se
drug interactions
Duloxetine less ____than...
Levimilnacioran more potent...
Milnacipran used for...
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SSRI
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SSRIs
Citalopram: highest toxicity
Fluvoxamine
Escitalopram
Paroxetine
Sertraline
Fluoxatine
Side Effects
Sexual Dysfunction
Increased risk of bleeding
Myocardial Infarction in overdose
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Topiramate & Lacosamide
Topiramate (Anticonvulsants) moa
Topiramate (Anticonvulsants) use
Topiramate (Anticonvulsants) Pharmacokinetics
Topiramate (Anticonvulsants) se
Topiramate (Anticonvulsants) drug interactions
Topiramate (Anticonvulsants) other
Lacosamide MOA
Lacosamide use
Lacosamide Pharmacokinetics
Lacosamide se
Lacosamide other
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Tricyclic Antidepressants
Tricyclic Antidepressants
TCA moa; use
TCA se
TCA drug interactions
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Tricyclic Antidepressants (TCAs) Indications
Indications
Major Depression
Bedwetting
Fibromyalgia
OCD
Drugs
-Iptyline or -Ipramine Suffix
Amitriptyline
Desipramine
Clomipramine
Imipramine
Nortriptyline
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Tricyclic Antidepressants (TCAs) Overview
Mechanism of Action
Blocks Serotonin and NE Reuptake
Lipid-soluble
Side Effects
Adverse CNS Effects
Anticholinergic
Antihistamine
Tri-C: Convulsion, Coma, Cardiotoxicity
Blocks Alpha1 Receptors
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2 mins
Valproic Acid
Indications
First Line Tonic-Clonic Seizure Treatment
Bipolar Disorder
Migraine Prophylaxis
Mechanism of Action
Increases GABA Concentration
Blocks Voltage-Gated Na+ Channels
Side Effect
GI Distress
Contraindication
Contraindicated in Pregnancy
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1 min
Valproic Acid (Valproate) Side Effects
V-A-L-P-R-O-A-T-E
Vomiting
Alopecia
Liver Toxicity
Pancreatitis/Pancytopenia
Retain Fat (Weight Gain)
Oedema (Edema)
Appetite Increase
Tremor
Enzyme Inhibitor (P450)
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2 mins

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