Janani Shared "Z Endo" - 47 Picmonics
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Z Endo
Gs protein receptors "cAMP" (FLAT CHAMP)
- adenylate cyclase -> cAMP -> PKA
- FSH
- LH
- ACTH
- TSH
- CRH
- hCG
- ADH (V2)
- MSH
- PTH
- Calcitonin
- GHRH
- glucagon
- H2
- epinephrine
cGMP Signaling Hormones (GOAT HAG)
- GnRH
- Oxytocin
- ADH (V1-receptor)
- TRH
- Histamine (H1-receptor)
- Angiotensin II
- Gastrin
- IP3
Enzyme-linked Receptors
- Receptor Guanylate Cyclase: ANP, BNP (membrane), Nitric Oxide (soluble)
- Receptor Tyrosine Kinase (RTK): Growth Factors | RET gene encodes RTK
- Tyrosine Kinase-associated Receptors
- PIGGLET Mnemonic
- PRL
- Immunomodulators
- GH
- G-CSF & EPO
- TPO
- JAK-STAT
glut transporter (DELETED)
- GLUT-1
- Placenta
- RBCs
- Cornea
- Brain
- Colon
- Kidney
- GLUT-2
- Islets of Langerhans
- Liver
- small intestine
- Glut-3
- Brain, placenta
- GLUT-5
- Spermatocytes, GI tract
- GLUT-4
- adipose tissue, striated muscle
- Kidney
Regulation of phosphofructokinase-1
- Fasting State
- Increased Glucagon (cAMP)
- Phosphorylate & activate Fructose Bisphosphatase-2 (FBPase2)
- gluconeogenesis
- Fed State
- Increased Insulin (decreased cAMP)
- Phosphofructokinase-2
- Glycolysis
- F-1,6-Bpase is upregulated by citrate, ATP, acetyl coA
- PFK-2 activates fructose 2,6 BP, which activates PFK1
dopamine agonists
- Ergots
- Bromocriptine
- non ergots
- pramipexole
- ropinirole
17 Alpha Hydroxylase Deficiency
- Decreased Cortisol
- Decreased Sex Hormones
- Increased Mineralocorticoids (DOC)
- Hypertension
- Hypokalemia
- XY Externally Phenotypic Female
- No Internal Reproductive Structures Due to Mullerian Inhibitory Factor
- XX Externally Phenotypic Female
- Sexual Infantilism
2 mins
21 Hydroxylase Deficiency
- Pathophysiology
- Decreased Cortisol
- Increased 17 Hydroxyprogesterone
- Decreased Aldosterone
- Signs and Symptoms
- Hypotension
- Increased Renin
- Hyperkalemia
- Female Pseudohermaphroditism
2 mins
11 Beta-Hydroxylase Deficiency
- Pathophysiology
- Decreased Cortisol
- Decreased Aldosterone
- Increased Sex Hormones
- Increased 11 Deoxycorticosterone (11 DOC)
- Signs and Symptoms
- Hypertension
- Masculinization
1 min
Sheehan's Syndrome
- Postpartum Pituitary Gland Necrosis
- Agalactorrhea
- Amenorrhea
- Secondary Hypothyroidism with Cold Intolerance
1 min
Syndrome Of Inappropriate Antidiuretic Hormone (SIADH)
- Pathophysiology
- Hypersecretion of ADH
- Increased Sensitivity to ADH
- Signs & Symptoms
- Serum Hypoosmolality
- Coma and Seizure
- Dilutional Hyponatremia
- Cramps and Tremors
- Euvolemia
- Change in LOC
2 mins
Syndrome of Inappropriate Antidiuretic Hormone (SIADH) Pharmacologic Interventions
- Diuretics
- Hypertonic IV Fluids
- Demeclocycline
- Tolvaptan and Conivaptan
1 min
Hypothyroidism Assessment
- Assessment
- Weight Gain - Edema
- Lethargy
- Cold Intolerance
- Bradycardia
- Hypertension
- Brittle Nails and Dry Skin
- Constipation
- Goiter
- Prolonged Menses
- Slowed Thinking
- Diagnostic Tests
- Decreased Free T4
- Increased TSH
2 mins
Hypothyroidism Intervention
- Medications
- Levothyroxine (Synthroid)
- Liothyronine (Cytomel)
- Complication
- Myxedema Coma
- Nursing Considerations
- Lifelong Replacement Hormone
- Monitor Vital Signs
- Fluids and Fiber
- Low Calorie, Low Fat Diet
- Medication Education
- No Switching Brands
2 mins
Congenital Hypothyroidism (Cretinism)
- Cause
- Thryoid dysgenesis
- The 6 P's of congenital hypothyroidism
- 6 P's
- Poor brain development
- Pot-bellied
- Pale
- Puffy face
- Protruding Umbilicus
- Protuberant Tongue
Hyperthyroidism Assessment
- Assessment
- Heat Intolerance
- Exophthalmos
- Warm, Moist Skin and Silky Hair
- Tremors
- Goiter
- Diarrhea
- Weight Loss
- Tachycardia
- Hypertension
- Amenorrhea
- Diagnosis
- Decreased TSH with Elevated Free T4
- Radioactive Iodine Uptake (RAIU)
2 mins
Hyperthyroidism Interventions
- Drug Therapy
- Propylthiouracil (PTU)
- Methimazole (Tapazole)
- Iodine
- Beta Blockers
- Other Therapies
- Radioiodine Ablation
- Thyroidectomy
- Complications
- Thyrotoxicosis
- Post-Surgery Hypocalcemia
2 mins
Graves' Disease Characteristics
- Women 20-40 years old
- Pathophysiology
- Anti-TSH Receptor Antibodies
- Symptoms
- Ophthalmopathy
- Exophthalmos
- Hyperthyroidism
- Goiter
- Pretibial Myxedema
1 min
Graves' Disease Labs and Treatment
- Labs
- Decreased TSH
- Increased T3
- Increased T4
- Radioactive Iodine Uptake (RAIU)
- Treatment
- Beta blocker
- Methimazole
- Radioiodine Ablation
1 min
Hashimoto's Thyroiditis
- Symptoms
- Hypothyroidism with Bouts of Hyperthyroidism
- Enlarged, Nontender Thyroid
- Mechanism
- Autoimmune
- Anti-Thyroid Peroxidase (TPO)
- Anti-Thyroglobulin
- Lab Findings
- Hurthle Cells
- Lymphoid Follicles
- Associations
- HLA-DR5 and HLA-DR3
- Increased Risk Of Non-Hodgkin Lymphoma
2 mins
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