Andrew Shared "Antiviral Medications D&D4" - 5 Picmonics

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Antiviral Medications D&D4

Zanamivir (Relenza) and Oseltamivir (Tamiflu)
Indications
Influenza A and B
Treatment and Prophylaxis
Mechanism
Inhibits Release of New Virus
Inhibits Influenza Neuraminidase
1 min
Foscarnet
Indications
CMV Retinitis
Acyclovir-resistant HSV
Mechanism
Does Not Require Activation (by Viral Kinase)
Inhibits Viral DNA Polymerase
Pyrophosphate Analog
Resistance through Mutated DNA Polymerase
Side Effects
Nephrotoxicity
Electrolyte Abnormalities
Hypokalemia
Hypocalcemia
Hypomagnesemia
2 mins
Ganciclovir
Indications
Cytomegalovirus (CMV)
Immunocompromised
Mechanism
Guanosine Analog
Disrupts DNA Synthesis
Inhibits Viral DNA Polymerase
Side Effects
Hematologic Effects
Nephrotoxicity
1 min
Cidofovir
Indications
CMV Retinitis
Acyclovir-resistant HSV
Mechanism
Inhibits Viral DNA Polymerase
Side Effects
Nephrotoxicity
Administer with Probenecid and IV Saline
1 min
Ribavirin
Mechanism
Hypermutation in RNA Viruses
Inhibits Inosine Monophosphate Dehydrogenase
Indications
Hepatitis C
Viral Hemorrhagic Fevers
Respiratory Syncytial Virus (RSV)
Side Effects
Hemolytic Anemia
Teratogen
1 min

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