Ronnie Shared "Preso Picmonics" - 16 Picmonics
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Preso Picmonics
Cephalosporins Overview
- Mechanism of Action
- Beta Lactam Drug
- Inhibits Cell Wall Synthesis
- Bactericidal
- CLINICAL USE
- Meningitis
- MRSA
- Side Effects
- Hypersensitivity Reactions
- Vitamin K Deficiency
- Disulfiram Like Reaction with Alcohol
- Increased Nephrotoxicity of Aminoglycosides
- RESISTANCE
- Extended Spectrum Beta Lactamase
2 mins
1st Generation Cephalosporin
- Drug Names
- Cefazolin
- Cephalexin
- Indications (PEcK Mnemonic)
- Proteus mirabilis
- E. coli
- Klebsiella
- Gram-Positive Cocci
1 min
Penicillin
- Gram Positive
- Spirochetes
- Bind PBPs
- Block Transpeptidase Cross-linking of Cell Wall
- Activate Autolytic Enzymes
- Bactericidal
- Hypersensitivity Reactions
- Hemolytic Anemia
- Beta-lactamase Sensitive
2 mins
Aminopenicillin Uses
- Drug Names
- Ampicillin
- Amoxicillin
- Indications
- Shigella
- Haemophilus Influenzae
- Salmonella
- Listeria
- Enterococci
- Proteus Mirabilis
- E. Coli
1 min
Beta-1 Receptor
- Characteristics
- Gs Protein Class
- Increased Heart Rate
- Increased Contractility
- Increase Renin Release
- Increased Lipolysis
44 secs
P450 Inhibitors
- Quinidine
- Ciprofloxacin
- Isoniazid
- Grapefruit Juice
- Acute Alcohol Use
- Erythromycin (Macrolide)
- Indinavir
- Cimetidine
- Sulfonamides
- Ketoconazole
- Amiodarone
2 mins
P450 Inducer
- Griseofulvin
- Phenytoin
- Carbamazepine
- Rifampin
- Barbiturates
- Chronic Alcohol Use
- St. John's Wort
51 secs
Ganciclovir
- Indications
- Cytomegalovirus (CMV)
- Immunocompromised
- Mechanism
- Guanosine Analog
- Disrupts DNA Synthesis
- Inhibits Viral DNA Polymerase
- Side Effects
- Hematologic Effects
- Nephrotoxicity
1 min
Acyclovir (Zovirax)
- Mechanism
- Guanosine Analog
- Inhibits Viral Replication
- Thymidine Kinase Activation
- Indications
- Herpes Simplex Virus (HSV)
- Varicella Zoster Virus (VZV)
- Side Effects (Oral)
- Headache
- GI Distress
- Side Effects (IV)
- CNS Toxicity
- Nephrotoxicity (Crystalline Nephropathy)
- Considerations
- Prevents Recurrent Episodes
- Slow IV Infusion
2 mins
Alteplase
- Mechanism
- Tissue Plasminogen Activator
- Indications
- Thrombosis
- Side Effects
- Bleeding
- Contraindications
- Intracranial Hemorrhage
- Internal Hemorrhaging
- Considerations
- Minimize Bleeding
- Monitor for Shock
- Antidote
- Aminocaproic Acid
2 mins
Heparin Mechanisms
- Mechanism of Action
- Short Half-life
- Antithrombin Activation Cofactor
- Decrease Thrombin, Factor Xa
- Side Effects
- Bleeding
- Heparin Induced Thrombocytopenia (HIT)
- Antidote
- Protamine Sulfate
2 mins
NRTIs for HIV (Drug Names)
- Nucleoside Analog
- DEALSZ
- Didanosine (DDI)
- Emtricitabine (FTC)
- Abacavir (ABC)
- Lamivudine (3TC)
- Stavudine (d4T)
- Zidovudine (ZDV)
- Nucleotide Analog
- Tenofovir (TDF)
2 mins
NNRTI Drug Names
- Nevirapine (Viramune)
- Rilpivirine (Edurant)
- Delavirdine (DLV, Rescriptor)
- Efavirenz (EFV, Sustiva)
- Etravirine (ETR, Intelence)
54 secs
Hydroxyurea
- Mechanism
- Inhibits Ribonucleotide Reductase
- Decreased DNA Synthesis
- S-phase Specific
- Indications
- Melanoma
- Chronic Myelogenous Leukemia (CML)
- Sickle Cell Disease
- Through Increased HbF (Fetal Hemoglobin)
- Side Effects
- Myelosuppression
- GI Distress
2 mins
Vitamin K
- Sources
- Dark Green Leafy Vegetables
- Synthesized by Intestinal Flora
- Mechanism
- Activated by Epoxide Reductase
- Gamma Carboxylation of Glutamate
- Activation of Clotting Factors II, VII, IX, X, Protein C and S
- Considerations
- Deficiency with Broad Spectrum Antibiotics
- Neonatal Hemorrhage with Increased PT and aPTT
- Warfarin is a Vitamin K Antagonist
4 mins
Sturge Weber Syndrome
- Pathophysiology
- GNAQ Gene
- Signs and Symptoms
- Port Wine Stain
- Arterial Venous Malformation
- Leptomeningeal Angiomas
- Intellectual Disability
- Seizures
- Pheochromocytoma
- Glaucoma
- Tram-Track Calcifications
3 mins
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