Amy Shared "Central nervous System stimulants and related drugs" - 4 Picmonics
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Central nervous System stimulants and related drugs
Attention Deficit Hyperactivity Disorder (ADHD)
Mechanism of Action
Increase Catecholamines at Synaptic Cleft
Potential for Abuse
Methylphenidate HCL (Ritalin/Adderall)
NDRI (norepinephrine-dopamine reuptake inhibitor)
Contraindicated with Tic Disorders
Administer after Breakfast
Monitor Weight and Growth
Not a paradoxical reaction
Short term use: 3-6 months
Can combine with topiramate (combo is Qsymia)
FX: Fetal toxicity (cleft lip/palate)
Topiramate is GABA receptor modulator
Short Half Life
Blocks Adenosine Action
Exocytosis Of Neurotransmitter
Blocks histamine release
Insomnia, tachycardia, diarrhea
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