Brittany Shared "Pharmacology 1" - 33 Picmonics

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Pharmacology 1

Alpha Agonists
-RINE suffix
Norepinephrine
Hypotension
Phenylephrine
Hypotension
Congestion
Ephedrine
Congestion
Urinary Incontinence
Hypotension
Epinephrine
Anaphylaxis and Asthma
Hypotension
1 min
Nonselective Alpha-Blockers
Indications
Phentolamine
Reversible
Pheochromocytoma (Diagnosis)
Hypertensive Crisis
Phenoxybenzamine
Pheochromocytoma (Treatment)
Side Effects
Orthostatic Hypotension
Reflex Tachycardia
2 mins
Selective Alpha-1 Blockers
"-osin" suffix
Mechanism of Action
Blocks Alpha1 Receptors
Indications
Hypertension
Benign Prostatic Hyperplasia (BPH)
Side Effects
Syncope
Orthostatic Hypotension
1 min
Alpha-2 Agonists (Sympathoplegics)
Indications
Hypertension
Renal disease
Mechanism of Action
Centrally acting Alpha-2 Agonist
Drugs
Clonidine
Rebound Hypertension
Alpha-Methyldopa
Pregnancy
Coombs (+) Hemolytic Anemia
SLE Like Syndrome
2 mins
Selective Alpha-2 Blockers
Mirtazapine
Indications
Depression Treatment
Mechanism of Action
Blocks Alpha2 Receptor
Antagonist at 5-HT receptors
Side Effects
Sedation
Weight gain
Increased Serum Cholesterol
1 min
Beta-1 Agonists
Dobutamine
Heart Failure
Cardiac Stress Test
Isoproterenol
Bradyarrhythmias
Torsades de Pointes
1 min
Beta-2 Agonists
Short-term Treatment
Terbutaline
Asthma
Tocolysis
Albuterol
Asthma
Long-term Treatment
Salmeterol
Asthma
Chronic Obstructive Pulmonary Disease (COPD)
3 mins
Cardiovascular Effects of Beta-Blockers
Cardiac Myocytes and Vasculature
Decrease cAMP
Decreases SA and AV Node Conduction Velocity
Lower Blood Pressure
Decrease O2 Consumption
Decreases Mortality Post-MI
2 mins
Selective Beta-1 Blockers
Characteristics
"-olol" Suffix
Drug Names
Beta-1 selective
Atenolol
Esmolol
Metoprolol
Partial Beta agonists
Acebutolol
1 min
CNS Stimulants
Indications
Attention Deficit Hyperactivity Disorder (ADHD)
Obesity
Mechanism of Action
Increase Catecholamines at Synaptic Cleft
Increase Norepinephrine
Increase Dopamine
Drug Names
Methylphenidate (Ritalin)
Methamphetamine
Side Effect
Potential for Abuse
56 secs
Phenylephrine
Mechanism of Action
Alpha-1 Agonist
Indications
Mydriatic
Rhinitis
Hypotension
Decreased Chronotropy and Inotropy
2 mins
Systemic Effects of Beta-Blockers
Respiratory
Bronchoconstriction
Metabolic
Decreased Insulin
Decreased Glycolysis and Lipolysis
Eye
Reduces Intraocular Pressure
1 min
Nonselective Beta-Blockers
"-olol" Suffix
Nonselective
Propranolol
Timolol
Nadolol
Partial β Agonist
Pindolol
Nonselective β with α Blocking
Carvedilol
Labetalol
2 mins
Beta Blockers
"-olol" suffix
Mechanism
Decreases Heart Rate and Contractility
Decreases Peripheral Vascular Resistance
Decreases Renin Release
Indications
Hypertension
Heart Failure
Angina Pectoris
Contraindications
Asthma and Heart Block Patients
Nursing Considerations
Assess Blood Pressure and Heart Rate
Masking Signs of Hypoglycemia
Do Not Stop Abruptly
2 mins
Tyramine
Normally degraded by monoamine oxidase (MAO)
Levels increase in patients taking MAOIs
Displaces norepinephrine from presynaptic vesicles
Strong indirect sympathomimetic effect
Hypertensive crisis
Give phentolamine to patients on MAOIs who love their wine n' cheese
Wine and cheese syndrome
Dopamine
Heart failure
first defence
Severe Hypotension
Low Dose of Dopamine
renal Blood flow
kidney
Beta 1 Receptor Stimulated
Medium Doses
Inotropic Effects
High Doses
Alpha Receptor Stimulated
Vasoconstriction
Angina
Arrhythmia
Pheochromocytoma
Selective Serotonin Reuptake Inhibitor (SSRI) Overview
Indications
Depression
Anxiety
Mechanism of Action
Selective Serotonin Reuptake Inhibitors
Drugs
Paroxetine
Sertraline
Escitalopram
Fluoxetine
Side Effects
Sexual Dysfunction
Serotonin Syndrome
Treat with Cyproheptadine
2 mins
Fluoxetine (Prozac)
Mechanism of Action
Inhibits Reuptake of Serotonin
Indications
Depression
Side Effects
Sexual Dysfunction
CNS Stimulation
Weight Changes
Serotonin Syndrome
Contraindications
No MAO-Is
No Anticoagulants / Antiplatelets
Considerations
Suicide Risk
Delayed Onset of Action
2 mins
Serotonin Norepinephrine Reuptake Inhibitors (SNRIs)
Indications
Depression
Diabetic Peripheral Neuropathy
Duloxetine
Panic and Anxiety
Venlafaxine
Mechanism of Action
Inhibits Reuptake of Serotonin and NE
Side Effects
Hypertension
Insomnia
Nausea and Vomiting
Decreased Libido
1 min
Bupropion
Indications
Depression
Smoking Cessation
Mechanism of Action
Increase Dopamine and NE
Side Effects
Stimulant Side Effects
Seizure
1 min

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