Cole Shared "Neuro-Pharmacology 2" - 22 Picmonics
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Neuro-Pharmacology 2
Sumatriptan
- Mechanism of Action
- Short Half-Life
- 5-HT Agonist
- Inhibits Trigeminal Nerve Activation
- Induces Vasoconstriction
- Indications
- Migraine
- Cluster Headache
- Side Effects
- Increased Risk of Serotonin Syndrome
- Paresthesias
- Coronary Vasospasm
- Contraindication
- Prinzmetal's Angina
- Coronary Artery Disease (CAD)
3 mins
Topiramate
- Indications
- Seizure Treatment
- Migraine Prophylaxis
- Mechanism of Action
- Increase GABA Action
- Blocks Voltage-Gated Na+ Channels
- Side Effects
- Kidney Stones
- Weight Loss
- Sedation
1 min
Nonselective Beta-Blockers
- "-olol" Suffix
- Nonselective
- Propranolol
- Timolol
- Nadolol
- Partial β Agonist
- Pindolol
- Nonselective β with α Blocking
- Carvedilol
- Labetalol
2 mins
Nonbenzodiazepine Hypnotics
- Indications
- Insomnia
- Mechanism of Action
- Short Half-Life
- Acts on BZ1 GABA receptor
- Less dependence
- Drugs
- Zolpidem (Ambien)
- Side Effects
- Ataxia, confusion
- Antidote
- Flumazenil for Overdose
1 min
Benzodiazepines Overview
- Indications
- First Line for Status Epilepticus
- Anesthesia Induction
- Anxiety
- Eclampsia
- Detoxification
- Mechanism of Action
- '-zepam' and '-zolam" Suffix
- Increase Frequency of Cl- Channel Opening
- Side Effects
- Decrease REM Sleep
- CNS Depression
- Dependence
- Antidote
- Flumazenil for Overdose
2 mins
Benzodiazepine Antidote
- Antidote
- Flumazenil
40 secs
Selective Serotonin Reuptake Inhibitor (SSRI) Overview
- Indications
- Depression
- Anxiety
- Mechanism of Action
- Selective Serotonin Reuptake Inhibitors
- Drugs
- Paroxetine
- Sertraline
- Escitalopram
- Fluoxetine
- Side Effects
- Sexual Dysfunction
- Serotonin Syndrome
- Treat with Cyproheptadine
2 mins
Tricyclic Antidepressants (TCAs) Indications
- Indications
- Major Depression
- Bedwetting
- Fibromyalgia
- OCD
- Drugs
- -Iptyline or -Ipramine Suffix
- Amitriptyline
- Desipramine
- Clomipramine
- Imipramine
- Nortriptyline
2 mins
Monoamine Oxidase Inhibitors (MAO-Is)
- Indications
- Atypical Depression
- Mechanism of Action
- Increase Levels of Amine Neurotransmitters
- Drugs
- "Takes Pride In Shanghai"
- Tranylcypromine
- Phenelzine
- Isocarboxazid
- Selegiline
1 min
Serotonin Norepinephrine Reuptake Inhibitors (SNRIs)
- Indications
- Depression
- Diabetic Peripheral Neuropathy
- Duloxetine
- Panic and Anxiety
- Venlafaxine
- Mechanism of Action
- Inhibits Reuptake of Serotonin and NE
- Side Effects
- Hypertension
- Insomnia
- Nausea and Vomiting
- Decreased Libido
1 min
Bupropion
- Indications
- Depression
- Smoking Cessation
- Mechanism of Action
- Increase Dopamine and NE
- Side Effects
- Stimulant Side Effects
- Seizure
1 min
Selective Alpha-2 Blockers
- Mirtazapine
- Indications
- Depression Treatment
- Mechanism of Action
- Blocks Alpha2 Receptor
- Antagonist at 5-HT receptors
- Side Effects
- Sedation
- Weight gain
- Increased Serum Cholesterol
1 min
Lithium
- Indications
- Bipolar Disorder
- Mechanism of Action
- Mood Stabilizer
- Unknown Mechanism
- Side Effects
- Nephrogenic Diabetes Insipidus
- Hypothyroidism
- Movement (Tremor)
- Heart Block
- Contraindication
- Pregnancy (Ebstein's Anomaly)
1 min
Valproic Acid
- Indications
- First Line Tonic-Clonic Seizure Treatment
- Bipolar Disorder
- Migraine Prophylaxis
- Mechanism of Action
- Increases GABA Concentration
- Blocks Voltage-Gated Na+ Channels
- Side Effect
- GI Distress
- Contraindication
- Contraindicated in Pregnancy
1 min
Opioids Overview
- Indications
- Pain
- Weaning
- Cough
- Diarrhea
- Mechanism of Action
- Agonists at Mu (μ), Kappa (Κ), and Delta (δ) Receptors
- Decrease Synaptic Transmission
- Side Effects
- Respiratory Depression
- Addiction
- Miosis
- Constipation
2 mins
Opioid Antidote
- Antidote
- Naloxone
29 secs
Alpha-2 Agonists (Sympathoplegics)
- Indications
- Hypertension
- Renal disease
- Mechanism of Action
- Centrally acting Alpha-2 Agonist
- Drugs
- Clonidine
- Rebound Hypertension
- Alpha-Methyldopa
- Pregnancy
- Coombs (+) Hemolytic Anemia
- SLE Like Syndrome
2 mins
Amphetamine Antidote
- Antidote
- Ammonium Chloride (NH4Cl)
- Acidify Urine
34 secs
Atypical Antipsychotics
- Indications
- Schizophrenia
- Mechanism of Action
- Unknown Mechanism
- Side Effects
- Seizures
- Prolonged QT Interval
- Agranulocytosis
- Weight Gain
- Fewer Extrapyramidal Side Effects
- Fewer Anticholinergic Side Effects
2 mins
Donepezil
- Indications
- Alzheimer's Disease
- Mechanism of Action
- Acetylcholinesterase Inhibitor
- Increased Acetylcholine
- Side Effects
- Nausea and Vomiting
- Dizziness
52 secs
