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FND
Direct Cholinomimetics
Muscarinic Agonists
Bethanechol
Bladder and Bowels
Methacholine
Bronchoconstriction
Pilocarpine
Contracts Ciliary Muscle and Pupillary Sphincter
Carbachol
Releases Intraocular Pressure
1 min
Atropine
Indications
Blocks DUMBBeLSS
Bradycardia
Side Effects
Skin Flushing
Increased Temperature
Dry Mouth
Cycloplegia
Disorientation
Mydriasis
1 min
Anticholinergics
B.O.AT.S Acronym
Benztropine
Parkinson's Disease
Oxybutynin
Decrease bladder spasms
Atropine
Mydriasis and Cycloplegia
Scopolamine
Motion Sickness
1 min
Anticholinergics Continued
Drugs
Glycopyrrolate
Reduces Airway Secretions
Ulcer Treatment
Ipratropium
Asthma and C.O.P.D
Dicyclomine
Hyoscyamine
Irritable Bowel Syndrome
1 min
Indirect Cholinomimetics
Acetylcholinesterase Inhibitors
Doesn't Cross BBB
Edrophonium
Myasthenia Gravis (Diagnosis)
Pyridostigmine and Neostigmine
Myasthenia Gravis (Tx)
Ileus
Crosses BBB
Physostigmine
Atropine Overdose
Glaucoma
Donepezil
Alzheimer's
2 mins
Acetylcholinesterase Inhibitor Antidote
Antidote
Atropine
Pralidoxime
1 min
Alpha 1 Receptor
Characteristics
Gq Subunit
Increase Vascular Smooth Muscle Contraction
Increase Pupillary Dilator Muscle Contraction
Increase Intestinal and Bladder Sphincter Muscle Contraction
1 min
Alpha 2 Receptor
Characteristics
Gi Subunit
Decrease Sympathetic Outflow
Decrease Insulin Release
Decrease Lipolysis
Increase Platelet Aggregation
Decrease Aqueous Humor Production
2 mins
Beta-1 Receptor
Characteristics
Gs Protein Class
Increased Heart Rate
Increased Contractility
Increase Renin Release
Increased Lipolysis
44 secs
Beta-2 Receptor
Characteristics
Gs Protein Class
Cardiopulmonary
Increased Heart Rate
Increased Contractility
Bronchodilation
Metabolic
Increased Lipolysis
Increased Insulin
Increased Glycogenolysis
Increased Cellular Potassium Uptake
Considerations
Increased Aqueous Humor Production
Vasodilation
Decrease Uterine Tone
2 mins
Dobutamine
Mechanism
Beta-1 Agonist
Inotropic
Indications
Heart Failure
Side Effects
Tachycardia
Arrhythmias
Considerations
Closely Monitor Patients
Other Meds May Increase Potency
1 min
Beta-2 Agonists
Short-term Treatment
Terbutaline
Asthma
Tocolysis
Albuterol
Asthma
Long-term Treatment
Salmeterol
Asthma
Chronic Obstructive Pulmonary Disease (COPD)
3 mins
Alpha Agonists
-RINE suffix
Norepinephrine
Hypotension
Phenylephrine
Hypotension
Congestion
Ephedrine
Congestion
Urinary Incontinence
Hypotension
Epinephrine
Anaphylaxis and Asthma
Hypotension
1 min
Alpha-2 Agonists (Sympathoplegics)
Indications
Hypertension
Renal disease
Mechanism of Action
Centrally acting Alpha-2 Agonist
Drugs
Clonidine
Rebound Hypertension
Alpha-Methyldopa
Pregnancy
Coombs (+) Hemolytic Anemia
SLE Like Syndrome
2 mins
Nonselective Beta-Blockers
"-olol" Suffix
Nonselective
Propranolol
Timolol
Nadolol
Partial β Agonist
Pindolol
Nonselective β with α Blocking
Carvedilol
Labetalol
2 mins
Selective Beta-1 Blockers
Characteristics
"-olol" Suffix
Drug Names
Beta-1 Selective
Atenolol
Esmolol
Metoprolol
Partial Beta agonists
Acebutolol
1 min
Selective Alpha-1 Blockers
"-osin" suffix
Mechanism of Action
Blocks Alpha1 Receptors
Indications
Hypertension
Benign Prostatic Hyperplasia (BPH)
Side Effects
Syncope
Orthostatic Hypotension
1 min
Nonselective Alpha-Blockers
Indications
Phentolamine
Reversible
Pheochromocytoma (Diagnosis)
Hypertensive Crisis
Phenoxybenzamine
Pheochromocytoma (Treatment)
Side Effects
Orthostatic Hypotension
Reflex Tachycardia
2 mins
Donepezil
Indications
Alzheimer's Disease
Mechanism of Action
Acetylcholinesterase Inhibitor
Increased Acetylcholine
Side Effects
Nausea and Vomiting
Dizziness
52 secs
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