Ashton Shared "RSM - Antifungals" - 19 Picmonics

With Picmonic, facts become pictures. We've taken what the science shows - image mnemonics work - but we've boosted the effectiveness by building and associating memorable characters, interesting audio stories, and built-in quizzing. Whether you're studying for your classes or getting ready for a big exam, we're here to help.

RSM - Antifungals

Amphotericin B
Indications
Systemic Mycosis
Fungal Meningitis
Last Resort for Protozoan infections
Mechanism
Polyene
Binds Ergosterol
Forms Membrane Pores
picmonic thumbnail
1 min
Amphotericin B Side Effects & Toxicity
Side Effects
Fever/Chills "Shake and Bake"
Nephrotoxicity
Milder with Liposomes
Hypotension
Anemia
IV Phlebitis
Arrhythmias
picmonic thumbnail
1 min
Azoles (Ketoconazole)
"-azole" suffix
Indications
Local and Less Serious Systemic Mycosis
Mechanism
Inhibits Ergosterol Synthesis
Inhibits P450
Side Effects
Liver Dysfunction
Inhibition of Testosterone Synthesis
picmonic thumbnail
1 min
Echinocandins
"-Fungin" suffix
Indications
Invasive Aspergillosis
Candida
Mechanism
Inhibits Cell Wall Synthesis
Inhibits Synthesis of Beta-glucan
Side Effects
GI Distress
Flushing
picmonic thumbnail
1 min
Flucytosine
Indications
Cryptococcus
Candida
Used in Combination with Amphotericin B or Azoles
Mechanism
Inhibits DNA and RNA Synthesis
Converted to 5-FU by Cytosine Deaminase
Side Effects
Bone Marrow Suppression
picmonic thumbnail
1 min
Antifungals for Superficial Infections
Polyene Drugs
Amphotericin
Nystatin (Candida but not Dermatophytes)
Natamycin
Allylamine Drugs
Terbinafine
Naftitine
Azole Drugs
Ketoconazole
Miconazole
Tioconazole
Fluconazole
Clotrimazole
Oropharyngeal & Vulvovaginal Candidiasis
Mitotic Inhibitor Drugs
Griseofulvin
Dermatophyte Localizations
Tinea corporis (Skin Ringworm)
Tinea Capitis (Scalp ringworm)
Tinea Cruris (Jock itch)
Tinea Pedis (Athlete's foot)
Tinea Ungum (nails)
Considerations
Topical for localized infections; Oral for Widespread or Scalp
Avoid Topical Corticosteroids
Story Mnemonic
picmonic thumbnail
Nystatin
Indications
Candidiasis
Vaginal
Oral
Cutaneous
Mechanism
Polyene
Binds Ergosterol
Forms Membrane Pores
Topical form of Amphotericin B
Side Effects
Rash
picmonic thumbnail
1 min
Terbinafine
Indications
Dermatophytosis
Onychomycosis
Mechanism
Inhibits Squalene Epoxidase
Side Effects
Hepatotoxicity
GI Distress
Taste Disturbances
Headache
picmonic thumbnail
2 mins
Griseofulvin
Mechanism
Disrupts Microtubules in Mitosis
Indications
Antifungal for Superficial Infections
Tinea and Ringworm
Side Effects
Teratogen
P450 Inducer
Confusion
Headache
picmonic thumbnail
2 mins
Candida Albicans
Fungi
Yeast with Pseudohyphae at 20 Degrees C
Germ Tube Formation at 37 Degrees C
Pruritic Vaginitis
White Cottage Cheese Discharge
Fiery Red Mucosa
Diabetics
Antibiotic Use
Esophageal Thrush in Immunocompromised
Diaper Rash
Endocarditis in IV Drug Users
picmonic thumbnail
2 mins
Chronic Mucocutaneous Candidiasis
Mechanism and Characteristics
T Cell Dysfunction
Candida Albicans
Signs and Symptoms
Infections of Skin
Infections of Mucous Membrane
Susceptible to HPV Infections like Condyloma Acuminatum
picmonic thumbnail
42 secs
Cryptococcus neoformans
Characteristics
Monomorphic
Encapsulated
Polysaccharide Capsule
Narrow-Based Buds
Latex Agglutination
Pigeons
India Ink
Mucicarmine stain
Signs and Symptoms
AIDS/Immunocompromised
Meningitis
Soap Bubble Lesions in Brain
Pneumonia
Treatment
Fluconazole
Flucytosine
Amphotericin
picmonic thumbnail
3 mins
Aspergillus fumigatus
Characteristics
Fungi
Monomorphic
Septate Hyphae
Branch at Acute Angles
Fruiting Bodies
Disease
Allergic Bronchopulmonary Aspergillosis (ABPA)
Eosinophilia
Increased IgE
Glucocorticoids +/- Azoles
Pulmonary Aspergillosis
TB Cavity
Lung Aspergilloma
Hemoptysis
Invasive Aspergillosis
AIDS/Immunocompromised
Chronic Granulomatous Disease
Hemorrhagic Infarction
Necrotizing Bronchopneumonia
Voriconazole +/- Caspofungin
picmonic thumbnail
3 mins
Histoplasmosis
Fungi
2-5 um
Yeast Cells within Macrophages
Starling Bird Poop
Bat Poop
Caves
Mississippi and Ohio River Valleys
Pneumonia
Caseating Granuloma
Erythema Nodosum
picmonic thumbnail
1 min
Coccidioidomycosis
Characteristics
Fungi
Dimorphic
Southwest
After earthquakes
Spherule
20-60 um
Signs and Symptoms
Pneumonia
Meningitis
Bone Infection
Skin infections
Erythema Nodosum
Granulomatous Inflammation
Caseous Necrosis
picmonic thumbnail
2 mins
Blastomyces
Characteristics
Fungi
Hyphae Form at 20°-25°C
Yeast Form at 37°C
Round Yeast
5-15 Micrometer (um or μm)
Single Broad-Based Buds
Thick Doubly-Refractive Walls
East of the Mississippi River and Around the Great Lakes
Signs and Symptoms
Pneumonia
Skin Infection
Bone Infection
Granulomatous Response
Treatment
Itraconazole
Amphotericin B
picmonic thumbnail
3 mins
Mucor and Rhizopus
Characteristics
Fungi
Irregular Non-septate Hyphae
Branching Wide Angles over 90 degrees
Signs and Symptoms
Leukemic Patients
Proliferate due to excess ketones and glucose
Diabetic Ketoacidosis (DKA)
Rhinocerebral frontal lobe abscess
Penetrate cribriform plate into brain
Black Necrotic Eschars on Face
picmonic thumbnail
2 mins
Paracoccidioido-mycosis
Fungi
Latin America
Common in Brazil
Budding yeast with captain wheel formation
40-50 um
Pneumonia
picmonic thumbnail
39 secs
Pityriasis Versicolor (Tinea versicolor)
Mechanism
Lipid-Dependent Fungus
Fatty Acids Damage Melanocytes
Malassezia Furfur
Hot, Humid Weather
Signs and Symptoms
Hypopigmentation
Hyperpigmented Patches
Diagnosis
Spaghetti and Meatball Appearance on KOH Prep
Fragmented Hyphae with Clusters of Yeast
Treatment
Topical or Oral Antifungals
Selenium Sulfide
Zinc
picmonic thumbnail
4 mins

Ace Your Medicine (MD/DO) Classes & Exams with Picmonic:

Over 1,180,000 students use Picmonic’s picture mnemonics to improve knowledge, retention, and exam performance.

Choose the #1 Medicine (MD/DO) student study app.

Picmonic for Medicine (MD/DO) covers information that is relevant to your entire Medicine (MD/DO) education. Whether you’re studying for your classes or getting ready to conquer the USMLE Step 1, USMLE Step 2 CK, COMLEX Level 1, or COMLEX Level 2, we’re here to help.

Works better than traditional Medicine (MD/DO) flashcards.

Research shows that students who use Picmonic see a 331% improvement in memory retention and a 50% improvement in test scores.

It's worth every penny