Daniel Shared "Reproductive System Part 1" - 64 Picmonics
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Reproductive System Part 1
Leuprolide
- Mechanism
- GnRH Agonist (Pulsatile Use)
- GnRH Antagonist (Continuous Use)
- Upregulates FSH And LH
- Downregulates FSH And LH
- Indications Pulsatile
- Infertility
- Indications Continuous
- Prostate Cancer
- Precocious Puberty
- Uterine Fibroids
- Endometriosis
- Side Effects
- Anti-androgenic Effects
2 mins
Selective Alpha-1 Blockers
- "-osin" suffix
- Mechanism of Action
- Blocks Alpha1 Receptors
- Indications
- Hypertension
- Benign Prostatic Hyperplasia (BPH)
- Side Effects
- Syncope
- Orthostatic Hypotension
1 min
Prostatitis
- Chronic Bacterial Prostatitis
- Acute Bacterial Prostatitis
- Types
- Sexually Transmitted Organisms
- E. Coli Infection
- Assessment
- Flu-Like Symptoms
- Perineal Pain
- Dysuria
- Sexual Dysfunction
- Recurrent UTIs
- Urinalysis
- Tender Boggy Prostate
- Management
- Antibiotics
- Considerations
- Chronic Prostatitis
3 mins
Acute Prostatitis
- Etiology
- Older Adult
- Escherichia coli
- Young Adult
- Chlamydia trachomatis
- Neisseria gonorrhoeae
- Signs and Symptoms
- Urinary Frequency and Urgency
- Dysuria
- Low Back Pain
- Warm, Tender, Swollen Prostate
- Treatment
- Treat Underlying Cause
1 min
Chronic Prostatitis
- Characteristic
- Onset > 3 Months
- Etiology
- Bacteria
- Non-bacteria
- Secondary Previous Infection
- Nerve Problems
- Chemical Irritation
- Signs and Symptoms
- Urinary Frequency and Urgency
- Dysuria
- Low Back Pain
- Warm, Tender, Enlarged Prostate
- Treatment
- Treat Underlying Cause
3 mins
Prostate Adenocarcinoma Characteristics and Presentation
- Characteristics
- Most Common Cancer in Men
- Screening Test if Suspicious
- Prostate Specific Antigen (PSA)
- Peripheral Zone
- Risk Factors
- African American
- Advanced Age
- Presentation
- Usually Asymptomatic
- Terminal Hematuria
- Urinary Retention or Incontinence
- Lower Back Pain
2 mins
17 Alpha Hydroxylase Deficiency
- Decreased Cortisol
- Decreased Sex Hormones
- Increased Mineralocorticoids (DOC)
- Hypertension
- Hypokalemia
- XY Externally Phenotypic Female
- No Internal Reproductive Structures Due to Mullerian Inhibitory Factor
- XX Externally Phenotypic Female
- Sexual Infantilism
2 mins
21 Hydroxylase Deficiency
- Pathophysiology
- Decreased Cortisol
- Increased 17 Hydroxyprogesterone
- Decreased Aldosterone
- Signs and Symptoms
- Hypotension
- Increased Renin
- Hyperkalemia
- Female Pseudohermaphroditism
2 mins
11 Beta-Hydroxylase Deficiency
- Pathophysiology
- Decreased Cortisol
- Decreased Aldosterone
- Increased Sex Hormones
- Increased 11 Deoxycorticosterone (11 DOC)
- Signs and Symptoms
- Hypertension
- Masculinization
1 min
5 Alpha Reductase Deficiency
- Autosomal Recessive
- Inability to Convert Testosterone to DHT
- Normal Internal Genitalia
- Ambiguous External Genitalia until Puberty
- Masculinization During Puberty with Growth of External Genitalia
- LH can be Increased
- Normal Estrogen, LH, and Testosterone levels
2 mins
Androgen Insensitivity (Complete)
- Defect in Androgen Receptor
- Phenotypically Female
- (46, XY)
- Female External Genitalia
- Rudimentary Vagina
- Scant Sexual Hair
- Testes Often in Labia Majora
- Testes Surgically Removed to Prevent Malignancy
- Increased Estrogen, Testosterone, and LH
- Absent Uterus and Fallopian Tubes
3 mins
Clomiphene
- Indications
- Infertility
- Polycystic Ovarian Syndrome (PCOS)
- Mechanism of Action
- Selective Estrogen Receptor Modulator (SERM)
- Hypothalamus
- Estrogen Antagonist
- Increased GnRH, LH and FSH Secretion
- Induction of Ovulation
- Side Effects
- Multiple Gestations
- Visual Disturbances
- Hot Flashes
2 mins
Aromatase Inhibitors
- Indications
- Estrogen Receptor-positive (ER+) Breast Tumors
- Systemic Metastases
- Drugs
- Reversible, non-steroid
- Letrozole
- Anastrozole
- Irreversible, steroid
- Exemestane
- Side Effects
- Osteoporosis
- Arthritis
1 min
Tamoxifen
- Mechanism of Action
- Selective Estrogen Receptor Modulator (SERM)
- Antagonist on Breast Tissue
- Indications
- ER-positive Breast Cancer
- Side Effects
- Decreased Risk of Osteoporosis
- Increased Risk of Endometrial Cancer
- Increased Risk of Venous Thromboembolism (VTE)
1 min
Raloxifene
- Mechanism of Action
- Selective Estrogen Receptor Modulator (SERM)
- Agonist in Bone
- Antagonist in Breast and Uterus
- Indications
- Osteoporosis
- Breast Cancer Prophylaxis
- Uterine Fibroids
- Side Effects
- Hot Flashes
- Thromboembolism
2 mins
Fibroadenoma
- Most Common Benign Breast Tumor
- Stromal Tumor
- Presentation
- Women under 40
- Small, firm mass
- Sharp Edges
- Increased tenderness and size with Estrogen
- Management
- Biopsy
1 min
Paclitaxel (Taxanes)
- Mechanism of Action
- Taxane
- Stabilizes Microtubules
- Indications
- Breast Cancer
- Ovarian Cancer
- Non-Small Cell Lung Cancer
- Kaposi Sarcoma (HHV-8)
- Side Effects
- Mucositis
- Myelosuppression
- Peripheral Neuropathy
- Hypersensitivity
- Alopecia
- Considerations
- Diphenhydramine (Benadryl)
2 mins
Trastuzumab
- Indications
- HER-2+ Breast Cancer
- Stomach Cancer
- Mechanism
- Monoclonal Antibody Against HER-2
- Inhibition of Cellular Signaling
- Cytotoxicity
- Side effects
- Cardiotoxicity
1 min
Gonorrhea
- Mechanism
- Neisseria gonorrhoeae
- Assessment
- Dysuria
- Yellowish-Green Discharge
- Increased Urinary Frequency
- Women Often Asymptomatic
- Interventions
- Ceftriaxone (IM)
- Chlamydia
- Doxycycline
- Azithromycin
- Considerations
- Treat Partners
2 mins
Chlamydia trachomatis
- Characteristics
- A to C
- Trachoma
- Follicular Conjunctivitis
- Blindness
- Africa
- L1 to 3
- Lymphogranuloma venereum
- Buboes
- Genital Ulcer
- D to K
- Urethritis and PID
- Neonatal Pneumonia
- Staccato Cough
- Neonatal Conjunctivitis
2 mins
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