Mike Shared "Unit IX - Immunologic Drugs - Pharmacology: Patient Centered Nursing Process 9th Ed" - 25 Picmonics
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Unit IX - Immunologic Drugs - Pharmacology: Patient Centered Nursing Process 9th Ed
HIV CD4+ 100
- Signs and Symptoms
- Aspergillus fumigatus
- Cryptococcus neoformans
- Candida albicans (Esophagitis)
- Mycobacterium avium complex (MAC)
- Cytomegalovirus (CMV)
- Epstein-Barr virus (EBV) B-cell lymphoma
- Toxoplasma gondii
- Cryptosporidium
- Bartonella henselae
5 mins
HIV CD4+ 200
- Signs and Symptoms
- Herpes Simplex Virus (HSV)
- JC Virus
- Progressive Multifocal Leukoencephalopathy (PML)
- Pneumocystis Pneumonia
- (HIV) Dementia
- Histoplasmosis
3 mins
HIV CD4+ 500
- Signs and Symptoms
- Candida albicans (Oral Thrush)
- Kaposi's Sarcoma (HHV-8)
- Human Papillomavirus (HPV)
- Epstein-Barr Virus (Oral Hairy Leukoplakia)
3 mins
Human Immunodeficiency Virus (HIV) Assessment
- Assessment
- RNA Retrovirus
- CD4+ Helper T Cells
- Primary Infection
- Flu-like Symptoms
- Lymphadenopathy
- Symptomatic Stage
- Fatigue
- Diarrhea
- Unexplained Weight Loss
- White Spots on Tongue
- Persistent Fever
- Night Sweats
2 mins
Human Immunodeficiency Virus (HIV) Stages
- Primary Infection
- Within 3 Weeks
- Flu-like Symptoms
- Asymptomatic Stage
- Years
- Symptomatic Stage
- CD4+ < 500
- AIDS
- Opportunistic Infections
- CD4+ < 200
2 mins
Human Immunodeficiency Virus (HIV) Diagnosis
- HIV-1/2 Antigen/Antibody Immunoassay
- HIV-1/2 Antibody Differentiation Immunoassay
- Nucleic Acid Testing (NAT)
- Viral Load
- Polymerase Chain Reaction (PCR) in Neonates
3 mins
Human Immunodeficiency Virus (HIV) Interventions
- Interventions
- Adequate Nutrition
- Small Frequent Meals
- IV Hydration
- Emotional Support
- HIV Medications
- HAART
- Considerations
- Transmission Education
- Strict Asepsis for Invasive Procedures
- Treat Opportunistic Infections
2 mins
NRTIs (Nucleoside Reverse Transcriptase Inhibitors)
- Indications
- HIV
- Pregnancy and Prophylaxis given ZDV
- Mechanism
- Inhibit Nucleotide Binding to Reverse Transcriptase
- Chain Termination
- Require Phosphorylation
1 min
NRTIs for HIV (Drug Names)
- Nucleoside Analog
- DEALSZ
- Didanosine (DDI)
- Emtricitabine (FTC)
- Abacavir (ABC)
- Lamivudine (3TC)
- Stavudine (d4T)
- Zidovudine (ZDV)
- Nucleotide Analog
- Tenofovir (TDF)
2 mins
Tuberculosis Assessment
- Etiology
- Airborne Droplet
- Assessment
- 3 Week Productive Cough
- Night Sweats
- Chest Pain
- Fever
- Weight Loss
- Fatigue
- Diagnosis
- Chest X-Ray
- Blood Tests
- Mantoux Skin Test
- 3 Positive Sputum Tests
1 min
Cryptosporidium
- Characteristics
- Protozoa
- Ingestion of Oocysts in Food or Water
- Acid Fast Cysts
- Signs and Symptoms
- Outbreaks of Diarrhea from Contaminated Water Supply
- Mild Disease in Non-immunocompromised
- Severe Diarrhea in AIDS
- Treatment
- Nitazoxanide for Immunocompetent
2 mins
Cytomegalovirus (CMV)
- Characteristics
- Enveloped
- Double Stranded DNA
- Herpesvirus 5
- Diagnosis
- Non Heterophile Antibodies
- Owl's eye inclusions
- Signs and Symptoms
- Congenital TORCH infection
- Mononucleosis
- Pneumonia
- AIDS retinitis and esophagitis
- Infection in transplant recipients
2 mins
Tacrolimus (Prograf) Overview
- Mechanisms
- Immunosuppressant
- Inhibits Calcineurin, Decreasing IL-2
- Indications
- Transplant Rejection
- Atopic Dermatitis
- Considerations
- Increased Lymphoma Risk
- Avoid Grapefruit Juice
1 min
Tacrolimus (Prograf) Side Effects
- Nephrotoxicity
- Neurotoxicity
- GI Distress
- Infection
- Hypertension
- Hyperkalemia
- Hyperglycemia
1 min
Cyclosporine (Sandimmune) Overview
- Mechanism
- Immunosuppressant
- Inhibits Calcineurin, Decreasing IL-2
- Indications
- Prevent Transplant Rejection
- Psoriasis
- Rheumatoid Arthritis
- Considerations
- Monitor Plasma Levels
- Avoid Grapefruit Juice
- Increased Risk of Lymphoma
2 mins
Cyclosporine (Sandimmune) Side Effects
- Side Effects
- Nephrotoxicity
- Hepatotoxicity
- Infection
- Hypertension
- Hirsutism
- Tremor
- Hyperkalemia
- Hypomagnesemia
- Gingival Hyperplasia
1 min
Prednisone (Glucocorticoids)
- Mechanism
- Glucocorticoid
- Indications
- Inflammatory Conditions
- Organ Transplant Rejection
- Side Effects
- Cataracts and Glaucoma
- Cushing's Syndrome
- Osteoporosis
- Immunosuppression
- Hyperglycemia
- Ulcers
- Considerations
- Adrenal Insufficiency
- Taper Gradually
2 mins
Kidney Transplant
- Indications
- End Stage Renal Disease (ESRD)
- Considerations
- Selective Candidacy
- Close Compatibility
- Immunosuppressants
- Monitor for Rejection
- Monitor for Infection
- Monitor Urine Output
2 mins
Pneumocystis jirovecii
- Fungi
- AIDS/Immunocompromised
- Fever
- Hypoxemia
- Bronchoalveolar Lavage
- Biopsy
- Methenamine Silver Stain
- Saucer/cup shaped yeast forms
- Diffuse interstitial pneumonia CXR
- TMP-SMX
- Start prophylaxis when CD4 drops under 200
1 min
Nystatin
- Indications
- Candidiasis
- Vaginal
- Oral
- Cutaneous
- Mechanism
- Polyene
- Binds Ergosterol
- Forms Membrane Pores
- Topical form of Amphotericin B
- Side Effects
- Rash
1 min
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