The epidermis is the outside layer of the skin, typically associated with preventing damage to the body.
Keratinocytes are barrier cells that protect the body from environmental damage. The damage can come from pathogens, UV radiation, heat, water loss and other external conditions.
The skin gets its color from melanocytes, which are found at the bottom of the epidermis and produce melanin. Melanin also helps protect the body from UV radiation.
Dendritic cells are antigen-presenting immune cells located in the epidermis that activate the adaptive immune response.
Merkel cells are involved in the body's sensation to touch and determination of shapes and textures of objects.
The dermis is the middle layer of the skin, which consists of connective tissue to reduce strain and stress on the body.
Sweat glands are located in the dermis, and they secrete water to help the body decrease temperature during fever, exercise or stress.
Hair follicles are rooted in the dermis, but extend all the way up to the epidermis. Hair follicles assist in thermoregulation.
The sebaceous glands secrete a waxy and oily substance onto the hair and skin, which provides a waterproofing as well as a lubricant.
The hypodermis is composed of connective tissue that attaches the skin to the skeleton. It is one of the locations of adipose tissue storage.
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