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Pediatrics | Physician Assistant School Study Aid
Neonatal Respiratory Distress Syndrome
- Cause/Mechanism
- Fetal Lung Immaturity
- Lack of Surfactant
- Assessment
- Respiratory Distress
- Nasal Flaring
- Retractions
- Grunting
- Interventions
- Surfactant
- Oxygen
- Mechanical Ventilation
- Considerations
- Total Parenteral Nutrition (TPN)
2 mins
Cystic Fibrosis Mechanisms
- Autosomal Recessive
- CFTR chromosome 7
- Cl- channel defect
- Decreased chloride secretion
- Increased Na and water reabsorption
- Increased Na and Cl in sweat
- Dehydration of mucous layers
2 mins
Cystic Fibrosis Symptoms and Complications
- Recurrent Pulmonary Infections
- Chronic Bronchitis
- Nasal Polyps
- Pancreatic Insufficiency
- Intestinal Obstruction
- Malabsorption and Diarrhea
- Vitamin Deficiencies
- Chronic Hepatic Disease
- Infertility in Males
1 min
Cystic Fibrosis Diagnosis and Treatment
- Diagnosis
- Sweat chloride test > 60 mmol/L
- Meconium Ileus
- Treatment
- N-acetylcysteine
- Antibiotic Prophylaxis
- Pulmonary Maintenance
- Lung transplant
- Vitamin Replacement
1 min
Asthma
- Obstructive lung disease
- Bronchial Hyperresponsiveness
- History of Atopic Disease
- Beta2 agonists
- Corticosteroids
- Curschmann's spirals
- Hypertrophy of smooth muscle
- Reversible
- Charcot Leyden crystals
- Methacholine challenge
- Wheezing
- Cough
- Initially decreased PaCO2
- Pulsus paradoxus
2 mins
Intermittent Asthma
- Diagnosis
- Symptoms (Bronchoconstriction) and Rescue Inhaler Use ≤ 2 / Week
- No Interference With ADLs
- Nighttime Awakening < 2 / Month
- > 80 % of Predicted FEV1
1 min
Persistent Mild Asthma
- Diagnosis
- Symptoms (Brochoconstriction) and Rescue Inhaler Use > 2 Days / Week
- Nighttime Awakening 3-4 / Month
- Greater or equal to 80 % of Predicted FEV1
1 min
Persistent Moderate Asthma
- Diagnosis
- Symptoms (Bronchoconstriction) and Rescue Inhaler Use Daily
- Nighttime Awakening > 1 / Week
- 60-80% Predicted FEV1
- FEV1/FVC Decreased 5%
2 mins
Persistent Severe Asthma
- Diagnosis
- Symptoms (Bronchoconstriction) and Rescue Inhaler Use: Multiple/ Day
- With Minimal Activity
- Nighttime Awakening: Nightly
- < 60% Predicted FEV1
- > 5% Decrease FEV1/FVC
2 mins
Stages of Asthma Treatments
- Intermittent Asthma
- Short-acting Inhaled Beta-Agonist
- Persistent Mild Asthma
- Low-Dose Inhaled Corticosteroid
- Montelukast (Leukotriene Receptor Antagonist)
- Cromolyn (Mast Cell Stabilizers)
- Theophylline
- Persistent Moderate Asthma
- Long-acting Inhaled Beta-Agonist
- Zileuton
- Low-Medium Dose Inhaled Corticosteroid
- Persistent Severe Asthma
- High-Dose Inhaled Corticosteroid
- Omalizumab (Allergies)
- Systemic Corticosteroids
3 mins
Croup (Laryngotracheobronchitis)
- Mechanism
- Parainfluenza Virus
- Assessment
- 3 Months to 3 Years
- Nighttime
- Barking Seal Cough
- Inspiratory Stridor
- Interventions
- Cool Humidified Air
- Dexamethasone
- Racemic Epinephrine
2 mins
Respiratory Syncytial Virus (RSV) Assessment
- Mechanism
- Viral Infection Affecting Epithelial Cells
- Signs and Symptoms
- Begins After a Upper Respiratory Infection
- Copious Secretions
- Coughing and Sneezing
- Wheezing
- Otitis Media or Conjunctivitis (Possible Ear or Eye Drainage)
- Poor Feeding
- Tachypnea
2 mins
Respiratory Syncytial Virus (RSV) Interventions
- Palivizumab (Synagis)
- Hospitalization
- Contact Precautions
- Oxygen
- Separate Room
- Maintain Fluid Intake
- Short-acting Beta-Agonist Bronchodilator
2 mins
Tracheoesophageal Fistula (TEF)
- Cause
- Esophageal Atresia
- Ends in Blind Pouch
- Assessment
- Coughing
- Choking
- Cyanosis
- Drooling
- Considerations
- NPO
- Surgical Emergency
- Aspiration Pneumonia
2 mins
Corynebacterium diphtheriae
- Characteristics
- Gram-Positive
- Bacillus
- Exotoxin
- ADP Ribosylation of Elongation Factor 2
- Beta Prophage
- Lysogeny
- Tellurite Agar
- Chinese Letters
- Metachromatic Blue Red Granules
- Aniline Stains Deeply Methylene Blue
- Signs and Symptoms
- Pseudomembranous Pharyngitis
- Lymphadenopathy
- Myocarditis
- Polyneuritis
3 mins
Bordetella pertussis
- Pathophysiology
- Gram-Negative
- Coccobacillus
- Bordet-Gengou Agar
- ADP Ribosylating AB Toxin
- Inhibits Gi to cause Increase in cAMP
- Signs AND Symptoms
- Lymphocytosis
- Increase in Insulin
- Catarrhal Phase is Infectious Period
- Paroxysmal Phase is Symptomatic Period
- Whooping Cough
- Treatment
- Macrolides
4 mins
Influenza Virus
- Characteristics
- RNA Virus
- Orthomyxovirus
- Enveloped
- Negative Sense
- 8 Segments
- Helical
- Hemagglutinin for Viral Entry
- Neuraminidase for Virion Release
- Genetic Shift
- Reassortment of genome to cause major change
- Genetic Drift
- Minor Antigenic Mutations
- Considerations
- Reye Syndrome with Aspirin Use
- Guillain-Barre Syndrome
3 mins
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