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Infectious Disease | Physician Assistant School Study Aid
Herpes Simplex Virus (HSV)
- Characteristics
- Enveloped
- Double Stranded DNA
- Linear
- Signs and Symptoms
- Type 1 HSV
- Gingivostomatitis
- Keratoconjunctivitis
- Encephalitis of Temporal Lobes
- Latent in Trigeminal Ganglia
- Type 2 HSV
- Genital Vesicles
- Neonatal Herpes
- TORCHES
- Latent in Sacral Ganglia
- Diagnosis
- Tzanck Test
- Multinucleated Giant Cells
- Cowdry A Inclusions
- Treatment
- Acyclovir
2 mins
Genital Herpes
- Mechanism
- Herpes Simplex Virus 1 and 2 (HSV)
- Assessment
- May Be Asymptomatic
- Oral or Genital Lesions
- Vesicles in Clusters
- Pain
- Flu-like Symptoms
- Antiviral Medications
- Acyclovir
- Valacyclovir
- Famciclovir
- Considerations
- Infectious During Recurrences
2 mins
Varicella Zoster Virus (VZV)
- Herpesvirus 3
- Characteristics
- Enveloped
- Double Stranded DNA
- Signs and Symptoms
- Chickenpox
- Pneumonia
- Encephalitis
- Trigeminal and Dorsal Root Ganglia
- Shingles
- Diagnosis
- Tzanck Test
- Multinucleated Giant Cells
- Cowdry A Inclusion
- Treatment
- Acyclovir
2 mins
Varicella (Chickenpox)
- Mechanism
- Varicella Zoster Virus (VZV)
- Signs and Symptoms
- Red Maculopapular Rash
- Vesicles Ooze and Crust
- Pruritus
- Centripetal
- Considerations
- Varicella Immunization
- Skin Care to Minimize Itching
- Isolate until Vesicles Crust
2 mins
Epstein Barr Virus
- Characteristics
- Herpesvirus 4
- Double Stranded DNA
- Linear
- Enveloped
- Signs and Symptoms
- Infectious Mononucleosis
- Virus Attaches to CD21 in B Cells
- Nasopharyngeal Carcinoma
- Burkitt's Lymphoma
- Hodgkin's Lymphoma
1 min
Epstein Barr Virus Mononucleosis
- Mononucleosis
- Fever
- Hepatomegaly
- Splenomegaly
- Pharyngitis
- Posterior Cervical Lymphadenopathy
- Atypical Lymphocytes
- Heterophile Antibodies
- Rash Develops if treated with Ampicillin
- Hodgkin's Lymphoma
2 mins
Infectious Mononucleosis
- Mechanism
- Herpes-like Viral Infection
- Signs and Symptoms
- Fatigue
- Fever
- Sore Throat
- Head and Body Aches
- Hepatomegaly and Splenomegaly
- Swollen Lymph Nodes in Neck and Armpits
- Rash
- Considerations
- Suppressed Immune Response
- Positive Monospot
2 mins
Cytomegalovirus (CMV)
- Characteristics
- Enveloped
- Double Stranded DNA
- Herpesvirus 5
- Diagnosis
- Non Heterophile Antibodies
- Owl's eye inclusions
- Signs and Symptoms
- Congenital TORCH infection
- Mononucleosis
- Pneumonia
- AIDS retinitis and esophagitis
- Infection in transplant recipients
2 mins
Cytomegalovirus (CMV) TORCH
- Signs and Symptoms
- Nonspecific TORCH symptoms
- Intrauterine Growth Restriction (Retardation)
- Deafness
- Microcephaly
- Seizures
- Periventricular Calcifications
- Petechial Rash
- Blueberry Muffin Rash
- Chorioretinitis
- Diagnosis
- Urine Viral Culture or PCR
2 mins
Roseola
- Exanthem
- Herpesvirus 6
- Enveloped
- Double Stranded DNA
- Linear
- Signs and Symptoms
- High Fevers Can Lead to Seizures
- Diffuse Macular Rash After Fever
1 min
Exanthema Subitum (Roseola Infantum)
- Mechanism
- Human Herpesvirus Type 6
- Signs and Symptoms
- Sudden High Fever
- Maculopapular, Nonpruritic Rash
- Considerations
- Febrile Seizures
- Tepid Baths
- Ibuprofen
- Acetaminophen
2 mins
Hepatitis B Virus Characteristics
- Hepadnavirus
- Enveloped
- Circular
- Partially Double-stranded DNA
- Has Reverse Transcriptase
- IV Drug Use
- Sex
- Maternal fetal routes
- 3 month incubation period
2 mins
Hepatitis B Virus Disease
- Can turn chronic
- < 10% of adults become chronic carriers
- 90% of newborns become chronic carriers
- Cirrhosis
- Hepatocellular carcinoma
- Membranous Glomerulonephritis
- Polyarteritis nodosa
- Serum sickness like syndrome
2 mins
Pox Virus
- Characteristics
- Enveloped
- Double-Stranded DNA
- Linear
- Non-Icosahedral
- Signs and Symptoms
- Smallpox
- Cowpox
- Molluscum Contagiosum
- Umbilicated Flesh-Colored Domed Lesions
1 min
Adenovirus
- Characteristics
- Non-enveloped
- Icosahedral
- Linear
- Double Stranded DNA
- Signs and Symptoms
- Pharyngitis
- Conjunctivitis
- Fever
- Summer Swimming
- Day Care Centers
- Acute Hemorrhagic Cystitis
- Pneumonia
1 min
Human Papillomavirus (HPV)
- Characteristics
- Non-enveloped
- Circular
- Double Stranded DNA
- Disease
- Warts 1, 2, 6, 11
- Condyloma acuminata
- Type 16, 18
- Cervical Carcinoma
- Penile Carcinoma
- AIDS/Immunocompromised
- Worsened by Smoking
- Diagnosis
- Koilocytic change in squamous epithelium
- Pyknotic Nuclei Surrounded by Clear Halo
- Treatment
- Vaccine Available
4 mins
Genital Warts - Condylomata Acuminata
- Mechanism
- Human Papillomavirus (HPV)
- Assessment
- Papillary Cauliflower Like Growths
- Bleeding
- Vaginal Discharge
- Interventions
- Wart Removal
- Trichloroacetic acid (TCA)
- Podophyllin resin
- Cryotherapy
- Considerations
- HPV Vaccine
- Cervical Cancer
2 mins
Cervical Cancer Screening
- Women aged 21-65 years old
- Pap smear every 3 years
- Women aged 30-65 years old
- Can opt for Co-testing (Pap Smear + HPV testing) every 5 years
- Identify lesions
- High grade lesions
- Cryotherapy
- Loop Excision
- Cold knife Conization
2 mins
Cervical Cancer Assessment
- Cause/Mechanism
- Human Papillomavirus (HPV)
- Assessment
- Metrorrhagia
- Leukorrhea
- Pain
- Abnormal Pap Test
- May Be Asymptomatic
- Considerations
- HPV Vaccine
2 mins
Polyomavirus
- Characteristics
- Non-enveloped
- Double-stranded DNA
- Circular
- Disease
- BK Virus
- Kidney Damage
- JC Virus
- Progressive Multifocal Leukoencephalopathy (PML)
- HIV/AIDS
- Oligodendrocyte
- Demyelination of CNS
4 mins
Parvovirus B19
- Characteristics
- DNA
- Single Stranded
- Linear
- Smallest DNA virus
- Non-enveloped
- Signs and Symptoms
- 5th Disease
- Slapped Cheek Rash in Children
- Erythema Infectiosum
- Hydrops Fetalis
- RBC aplasia
- Arthritis in Adults
- Aplastic Crisis in Sickle Cell
- Myocarditis
2 mins
Erythema Infectiosum (Fifths Disease)
- Mechanism
- Human Parvovirus B19
- Signs and Symptoms
- Cold-like Symptoms
- Three Stage Rash
- Slapped Face
- Maculopapular Red Spots on Trunk
- Rash Reappears
- Considerations
- Aplastic Crisis
- Joint Pain and Swelling
2 mins
Kaposi Sarcoma
- Characteristics
- Malignant Vascular Tumor
- Human Herpesvirus Type 8 (HHV-8)
- AIDS/Immunocompromised
- CD4+ < 500
- Presentation
- Multifocal Purple Lesions
- Skin
- Mucous Membranes
- Visceral Organs
- Diagnosis
- Spindle-shaped Cells
- Management
- Observation
- Chemotherapy
- Treat Underlying Disorder
3 mins
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