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Physician Assistant (PA)
First Aid for the USMLE Step 1 (2021)
Page 192 -

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First Aid for the USMLE Step 1 (2021) | Physician Assistant (PA) School Study Aid

Page 192 -
6 Picmonics to Learn | 12 mins
Tetracycline Drug Names and Indications
Drug Names
Fecally Eliminated
Can be Used in Renal Failure
Antidiuretic Hormone Antagonist
Borrelia burgdorferi
Helicobacter Pylori
Mycoplasma Pneumonia
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3 mins
Tetracycline Mechanism
Binds to 30 S to Prevent Attachment of Aminoacyl tRNA
Limited CNS Penetration
Divalent Cations Inhibit Absorption
Must Not Take with Milk, Antacids, Iron
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1 min
Tetracycline Toxicities
Inhibition of Bone Growth in Children
Discoloration of Teeth
GI Distress
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2 mins
Tigecycline (Tygacil)
Mechanism Of Action
Glycylcycline Antibiotic
Binds 30S Subunit
Inhibits Protein Synthesis
Severe Infections
Broad Spectrum Coverage
Anaerobic & Multidrug-Resistant Organisms
Deep Tissue Penetration
Side Effects
GI Distress
Severe Nausea and Vomiting
2nd Line Agent
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3 mins
Inhibits 50S Peptidyltransferase Activity
Rocky Mountain Spotted Fever in Pregnant Women
Side Effects
Aplastic Anemia
Gray Baby Syndrome due to Decreased UDP-Glucuronyl Transferase
Resistance Caused by Plasmid Encoded Acetyltransferase
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2 mins
Mechanism of Action
Binds 50S Ribosomal Subunit
Blocks Translocation
Anaerobic Infections above the Diaphragm
Aspiration Pneumonia
Lung Abscess
Side Effects
Can Cause Pseudomembranous Colitis
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1 min

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