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Pharmacology | Pharmacist (Pharm.D) School Study Aid
RhoGam [Rho(D) Immune Globulin]
- Indications
- Antepartum Prevention at 28 weeks
- Suppress Antibody Production
- Mechanism of Action
- Lysis of Fetal RBC in Maternal Bloodstream
- Side Effects
- Myalgia and Lethargy
- Considerations
- Negative Coombs Test
- Standard Dose 300 mcg
- Microdose 50 mcg
- Blood Product
2 mins
Magnesium Sulfate
- Mechanism
- Muscle Relaxant
- Indications
- Preterm Labor Contractions
- Preeclampsia
- Side Effects
- Warm Feeling
- Hypotension
- Decreased Deep Tendon Reflexes (DTRS)
- Decreased Respiratory Rate
- Decreased Urine Output
- Paralytic Ileus
- Antidote
- Calcium Gluconate
2 mins
Leuprolide
- Mechanism
- GnRH Agonist (Pulsatile Use)
- GnRH Antagonist (Continuous Use)
- Upregulates FSH And LH
- Downregulates FSH And LH
- Indications Pulsatile
- Infertility
- Indications Continuous
- Prostate Cancer
- Precocious Puberty
- Uterine Fibroids
- Endometriosis
- Side Effects
- Anti-androgenic Effects
2 mins
Methylergonovine (Methergine) and Ergotamine (Ergot Alkaloids)
- Mechanism
- Smooth Muscle Contraction
- Vasoconstriction
- Indications
- Migraine
- Postpartum Hemorrhage
- Side Effects
- Nausea and Vomiting
- Severe Hypertension
- Tachycardia
- Considerations
- 2nd Line Agent
2 mins
Oxytocin (Pitocin)
- Mechanism of Action
- Increase Uterine Contractions
- Indications
- Labor Induction
- Control Postpartum Hemorrhage
- Side Effects
- Uterine Rupture
- Water Intoxication
- Contraindications
- Fetal Lung Immaturity
- Cervix Not Ripened
- Active Genital Herpes Infection
- Considerations
- Use Lowest Dose
- IV Pump
3 mins
Carboprost (Hemabate)
- Mechanism
- Prostaglandin F2-alpha Analog
- Smooth Muscle Contraction
- Indications
- Postpartum Hemorrhage
- Abortion
- Side Effects
- GI Distress
- Hypertension
- Fever
- Bronchoconstriction
- Considerations
- Identify Cause of Fever
2 mins
Dinoprostone and Misoprostol
- Mechanism
- Prostaglandins
- Indications
- Promote Cervical Ripening
- Prevent GI Ulcers
- Medical Abortion
- Side Effects
- Fetal Distress
- Hyperstimulation of Uterus
- Considerations
- Vaginal Insertion
- Give Before Induction of Labor
2 mins
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