Benzodiazepines act on the central nervous system to produce sedation. Drowsiness is a symptom of benzodiazepine abuse. Chronic abuse may also lead to weakness and anorexia.
Confusion and slurred speech is a symptom of acute benzodiazepine toxicity. Chronic abuse may also manifest with symptoms of headaches and insomnia.
Individuals abusing benzodiazepines may have difficulty breathing and develop respiratory depression. Frequent assessment of the respiratory system is critical while monitoring the patient of benzodiazepine overdose.
Benzodiazepines act on the central nervous system to produce muscle relaxation. Hypotension is a symptom of benzodiazepine abuse.
Benzodiazepines act on the central nervous system to produce sedation. Excessive doses of benzodiazepine may lead to respiratory depression and coma.
Flumazenil (Romazicon) is a benzodiazepine receptor antagonist which reverses the effects of benzodiazepines by competitive inhibition at the benzodiazepine binding site on the GABA receptor. Chronic high dose abusers should be monitored while taking flumazenil, since the medication may precipitate seizures.
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