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Benzodiazepine Intoxication Assessment

Benz-dice with a Toxic-green-glow and Assess-man
Picmonic

Benzodiazepines are a group of medications that act on the central nervous system and cause sedation, muscle relaxation, and decreased anxiety. Examples of benzodiazepines include chlordiazepoxide (Librium), oxazepam (Serax), and diazepam (Valium). Symptoms of benzodiazepine abuse include confusion, drowsiness, and slurred speech. The individual may also experience hypotension, respiratory depression, and coma. Flumazenil (Romazicon) is a benzodiazepine receptor antagonist used to reverse the effects of benzodiazepine overdose.

6 KEY FACTS
Drowsiness
Sleepy-guy

Benzodiazepines act on the central nervous system to produce sedation. Drowsiness is a symptom of benzodiazepine abuse. Chronic abuse may also lead to weakness and anorexia.

Confusion
Confucius

Confusion and slurred speech is a symptom of acute benzodiazepine toxicity. Chronic abuse may also manifest with symptoms of headaches and insomnia.

Respiratory Depression
Deflated Lungs

Individuals abusing benzodiazepines may have difficulty breathing and develop respiratory depression. Frequent assessment of the respiratory system is critical while monitoring the patient of benzodiazepine overdose.

Hypotension
Hippo-BP

Benzodiazepines act on the central nervous system to produce muscle relaxation. Hypotension is a symptom of benzodiazepine abuse.

Coma
Comb

Benzodiazepines act on the central nervous system to produce sedation. Excessive doses of benzodiazepine may lead to respiratory depression and coma.

TREATMENT
Flumazenil (Romazicon)
Flute-mace-nail

Flumazenil (Romazicon) is a benzodiazepine receptor antagonist which reverses the effects of benzodiazepines by competitive inhibition at the benzodiazepine binding site on the GABA receptor. Chronic high dose abusers should be monitored while taking flumazenil, since the medication may precipitate seizures.

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