Master Fluoxetine (Prozac) with Picmonic for Nursing RN

With Picmonic, facts become pictures. We've taken what the science shows - image mnemonics work - but we've boosted the effectiveness by building and associating memorable characters, interesting audio stories, and built-in quizzing.

Fluoxetine (Prozac)

Flute-ox
Picmonic
Fluoxetine (Prozac) is a selective serotonin reuptake inhibitor (SSRI). Serotonin is a neurotransmitter that is involved in transmission of nerve impulses. SSRIs maintain mental balance in the brain by decreasing the reuptake of serotonin back into the presynaptic cell. This results in an increase of serotonin in the synaptic cleft which can bind to postsynaptic receptors and create more transmissions.
10 KEY FACTS
MECHANISM OF ACTION
Inhibits Reuptake of Serotonin
Inhibiting-chains on Silver-tonic Reuptake-tube

Fluoxetine (Prozac) selectively inhibits the reuptake of serotonin. The reuptake inhibition increases the available amount of serotonin, which is a monoamine neurotransimitter. Depression stems from a deficiency of this neurotransmitter (serotonin).

INDICATIONS
Depression
Depressed-emo

SSRI’s are primarily indicated for depression, which is believed to be a deficiency of freely available serotonin in the brain. Fluoxetine is also indicated for use in Obsessive Compulsive Disorder, Panic Disorder and Premenstrual Dysphoric Disorder. Many other SSRI’s are also indicated for additional uses in Generalized Anxiety Disorder, Post Traumatic Stress Disorder and Social Phobias.

SIDE EFFECTS
Sexual Dysfunction
Limp-weiner

A common side effect of SSRI’s is anorgasmia. These medications are sometimes used for the treatment of premature ejaculation because of this common side effect.

CNS Stimulation
CNS-brain with Stim-mule drink

Increased serotonin levels in some patients have an elevated response which may cause headache, nervousness, anxiety or insomnia. Some side effects are often alleviated by advising the patient to take the medication with food in the morning.

Weight Gain
Up-arrow Scale

Many patients may initially have weight loss while taking this medication. However, a side effect after long term treatment is weight gain.

Serotonin Syndrome
Silver-tonic Savage

Serotonin syndrome is a rare but serious side effect of any medication that increases the availability of serotonin. It can be remembered by the mnemonic HARM for Hypertension, Autonomic Instability (delirium), Rigidity (muscles) and Myoclonus (muscle jerking).  Other signs and symptoms include headache, hyperthermia, sweating, and agitation.

CONTRAINDICATIONS
No MAO-Is
Caution-tape Mao with Inhibiting-chains

Patients should not take monoamine oxidase inhibitors (MAO-Is) concurrently with SSRIs, as this increases the available pool of serotonin in the brain and increases the risk of developing serotonin syndrome.

No Anticoagulants / Antiplatelets
Caution-tape Ant-tie-clogs and Ant-tie-plates

SSRI’s decrease aggregation of platelets and increase GI bleeding risk up to 3 times. Patients should be advised to avoid anticoagulants and antiplatelets while taking these medications.

CONSIDERATIONS
Suicide Risk
Risk of Suicidal-jumper

Patients taking SSRIs may experience side effects, such as violent behavior, mania or aggression, which can increase suicidal thoughts or actions. Suicide risk increases during the initial phase of starting on the medication, and as the patient starts to feel better, they may have enough energy to carry out the suicide.

Delayed Onset of Action
Delayed On-switch

SSRIs most often take 1-3 weeks for therapeutic effects to occur with some patients taking up to 6 weeks. Recent studies suggest longer response times in patients with comorbid conditions or severe depression. Patients should be educated not to expect immediate effects of the medication.

Unlock all 10 facts & definitions with Picmonic Free!

JOIN FREE

Take the Fluoxetine (Prozac) Quiz

Picmonic's rapid review multiple-choice quiz allows you to assess your knowledge.

START QUIZ NOW

It's worth every penny

Our Story Mnemonics Increase Mastery and Retention

Memorize facts with phonetic mnemonics

Unforgettable characters with concise but impactful videos (2-4 min each)

Ace Your Nursing (RN) Classes & Exams with Picmonic:

Over 870,000 students use Picmonic’s picture mnemonics to improve knowledge, retention, and exam performance.

Choose the #1 Nursing (RN) student study app.

Picmonic for Nursing (RN) covers information that is relevant to your entire Nursing (RN) education. Whether you’re studying for your classes or getting ready to conquer your NCLEX®-RN, Hesi, ATI, TEAS test, Kaplan exams, we’re here to help.

Works better than traditional Nursing (RN) flashcards.

Research shows that students who use Picmonic see a 331% improvement in memory retention and a 50% improvement in test scores.