Master Syndrome of Inappropriate Antidiuretic Hormone (SIADH) Pharmacologic Interventions with Picmonic for Nursing RN

With Picmonic, facts become pictures. We've taken what the science shows - image mnemonics work - but we've boosted the effectiveness by building and associating memorable characters, interesting audio stories, and built-in quizzing.

Syndrome of Inappropriate Antidiuretic Hormone (SIADH) Pharmacologic Interventions

Inappropriate Ant-tie-die-rocket with Harmonica and Pills
Syndrome of Inappropriate Antidiuretic Hormone (SIADH) occurs when antidiuretic hormone (ADH) which normally regulates the retention of water by the kidneys is secreted in inappropriately increased amounts. Treatment of SIADH is aimed at correcting dilutional hyponatremia, closely monitoring for electrolyte and weight changes, as well as administering medications to decrease fluid retention. This card will cover the pharmacologic interventions, which include administration of diuretics, hypertonic IV fluids, and the medications Demeclocycline, Tolvaptan, and Conivaptal.

Diuretics are often administered to decrease sodium chloride reabsorption in the loop of henle. Loop diuretics specifically are effective in scenarios of high urine osmolarity. In severe cases of dilutional hyponatremia, diuretics may be supplemented with a hypertonic saline solution like 3% or 5% NaCl or a salt tablet.

Hypertonic IV Fluids
Hiker-tonic IV-bag

In severe cases of dilutional hyponatremia, a hypertonic IV fluid such as 3% or 5% sodium chloride (NaCl) may be administered. Be sure to implement careful monitoring.


This medication is given especially in situations where patients cannot tolerate hypertonic solutions. It is a derivative of the antibiotic tetracycline. This medication inhibits the action of ADH on the renal tubules which allows diuresis of water.

Tolvaptan and Conivaptan
Toll-captain and Cone-captain

The drugs tolvaptan (Samsca) and conivaptan (Vaprisol) are given because they are vasopressin receptor antagonists and work in the kidney to treat euvolemia-hyponatremia. Careful monitoring while administering these medications is important as rapid correction of serum sodium levels can cause irreversible neurological damage like central pontine myelinolysis.

Unlock all 4 facts & definitions with Picmonic Free!


Take the Syndrome of Inappropriate Antidiuretic Hormone (SIADH) Pharmacologic Interventions Quiz

Picmonic's rapid review multiple-choice quiz allows you to assess your knowledge.


It's worth every penny

Our Story Mnemonics Increase Mastery and Retention

Memorize facts with phonetic mnemonics

Unforgettable characters with concise but impactful videos (2-4 min each)

Ace Your Nursing (RN) Classes & Exams with Picmonic:

Over 870,000 students use Picmonic’s picture mnemonics to improve knowledge, retention, and exam performance.

Choose the #1 Nursing (RN) student study app.

Picmonic for Nursing (RN) covers information that is relevant to your entire Nursing (RN) education. Whether you’re studying for your classes or getting ready to conquer your NCLEX®-RN, Hesi, ATI, TEAS test, Kaplan exams, we’re here to help.

Works better than traditional Nursing (RN) flashcards.

Research shows that students who use Picmonic see a 331% improvement in memory retention and a 50% improvement in test scores.