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Overview of Antineoplastic Agents

Pharmacotherapeutics for Advanced Nursing Practice, 1st. Ed., Demler & Rhoads, 2018

Chapter 3: Antineoplastic Agents

Autoimmune Disorders

Which of the following is an indication for the use of Cyclophosphamide?

Cross-links DNA

What mechanism of action or pharmacological action is best associated with Cyclophosphamide?

Cyclophosphamide

Guanine N7 Position

Hemorrhagic Cystitis

During your assessment of a patient taking Cyclophosphamide which of the following side effects is most likely to be seen?

Indications

Leukemia

Lymphoma

Mechanism

Myelosuppression

Prevent with Mesna

Which of the following points are important regarding prevention of side effects associated with Cyclophosphamide?

Requires Bioactivation by Liver

Side Effects

Solid Tumors

AIDS/Immunocompromised

Which of the following groups of people are associated with Pneumocystis jiroveci?

Biopsy

Which of the following tests helps diagnose Pneumocystis jiroveci?

Bronchoalveolar Lavage

Diffuse interstitial pneumonia CXR

During your assessment of a patient with Pneumocystis jiroveci which of the following imaging findings is most likely to be seen?

Fever

During your assessment of a patient with Pneumocystis jiroveci which of the following is most likely to be seen?

Fungi

Pneumocystis jiroveci is most likely associated with which of the following types of pathogens?

Hypoxemia

Methenamine Silver Stain

Which type of stain is most likely associated with Pneumocystis jiroveci?

Pneumocystis jirovecii

Saucer/cup shaped yeast forms

Which microscopic finding or histological description is associated with Pneumocystis jiroveci?

Start prophylaxis when CD4 drops under 200

Which of the following is an important consideration regarding management of Pneumocystis jiroveci?

TMP-SMX

Which of the following medications is indicated as treatment & prophylaxis for Pneumocystis jiroveci?

Bone Marrow Ablation

Which of the following is an indication for Busulfan?

Busulfan

What mechanism of action or pharmacological action is best associated with Busulfan?

Hyperpigmentation

Which of the following side effects would most likely be associated with Busulfan?

Pulmonary Fibrosis

DNA Agents

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Overview of Antineoplastic Agents - Chapter 3: Antineoplastic Agents - Pharmacotherapeutics for Advanced Nursing Practice, 1st. Ed., Demler & Rhoads, 2018 - DNA Agents for Nursing RN

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