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Pharmacotherapeutics for Advanced Nursing Practice, 1st. Ed., Demler & Rhoads, 2018 | Registered Nurse (RN) School Study Aid


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Antibacterial Agents
17 Picmonics to Learn | 34 mins

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Aminoglycoside Overview
End in "-mycin"
GNATS
Gentamicin
Neomycin
Amikacin
Tobramycin
Streptomycin
Mechanism of Action
Bactericidal
Indications
Severe Gram Negative Infections
Bowel Surgery Prep
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1 min
Cephalosporins
Starts with "Cef-"
Mechanism of Action
Bactericidal
Indications
Gram-Positive and Gram-Negative Infections
Side Effects
Allergic Reactions
Thrombophlebitis
Bleeding
Contraindications
Renal Impairment
Considerations
Avoid IV Calcium with Ceftriaxone
No Alcohol
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2 mins
Imipenem and Meropenem (Carbapenems)
Mechanism
Carbapenems
Broad-spectrum Antibiotic
Bactericidal
Indications
Gram Positive and Gram Negative Infections
Side Effects
GI Distress
Suprainfections
Seizures
Considerations
Penicillin Allergy
IV or IM Route
Imipenem Combined with Cilastatin
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3 mins
Macrolides
Bacteriostatic
Erythromycin
Azithromycin
Clarithromycin
Bind to 23S rRNA of 50S subunit
Inhibit protein synthesis by blocking translocation
Gram-Positive Cocci
Atypical pneumonia
Chlamydia
Resistance by methylation of 23S rRNA binding
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1 min
Penicillin
Mechanism of Action
Weakens Cell Wall
Indications
Gram-Positive Infections
Prophylaxis
Side Effects
Pain at IM Injection Site
Allergic Reaction
Considerations
Skin Tests
Allergy ID
Medication Education
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2 mins
Ampicillin and Amoxicillin
Mechanism
Aminopenicillin
Broad Spectrum Penicillin
Indications
Gram-Positive and Some Gram-Negative Infections
Side Effects
Rash
Diarrhea
Considerations
No Effect Against Staph Aureus
Often combined with Beta Lactamase Inhibitor
Allergic Reaction
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2 mins
Fluoroquinolones
End in "-floxacin"
Mechanism of Action
Bactericidal
Indications
Variety of Infections
Side Effects
GI Distress
Photosensitivity
Achilles Tendon Rupture
Contraindications
Pregnancy
Children
Myasthenia Gravis
Considerations
Avoid Milk Products or Antacids
Slow IV Infusion
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2 mins
Silver Sulfadiazine (Silvadene) and Mafenide Acetate (Sulfamylon)
Mechanism
Topical Antimicrobial
Indications
Burns
Open Wound Care
Side Effects
Mafenide
Pain
Acidosis
Considerations
Administer Analgesic Prior to Wound Care
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1 min
Trimethoprim
Mechanism of Action
Bacteriostatic
Inhibits Bacterial Dihydrofolate Reductase
Causes Sequential Block of Folate Synthesis
Used in Combination with Sulfamethoxazole
Combination Used For Recurrent Urinary Tract Infections
Indications
Shigella
Salmonella
Pneumocystis Jiroveci Pneumonia
Side Effects
Decrease in Red and White Blood Cells
Alleviated with Leucovorin Rescue
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2 mins
Tetracyclines Overview
End in "-cycline"
Mechanism of Action
Bacteriostatic
Indications
Infectious Diseases
Acne
Periodontal Disease
Nursing Considerations
Avoid Milk, Antacids, Iron
Sunlight Protection
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1 min
Tetracycline Toxicities
Inhibition of Bone Growth in Children
Teratogen
Discoloration of Teeth
Photosensitivity
GI Distress
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2 mins
Tigecycline (Tygacil)
Mechanism Of Action
Glycylcycline Antibiotic
Binds 30S Subunit
Inhibits Protein Synthesis
Indications
Severe Infections
Broad Spectrum Coverage
Anaerobic & Multidrug-Resistant Organisms
Deep Tissue Penetration
Side Effects
GI Distress
Severe Nausea and Vomiting
Considerations
2nd Line Agent
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3 mins
Daptomycin (Cubicin)
Mechanism Of Action
Lipopeptide Antibiotic
Disrupts Cell Membrane
Causes Rapid Depolarization
Indication
Gram-Positive Cocci
MRSA
Side Effects
Myopathy
Rhabdomyolysis
Peripheral Neuropathy
Considerations & Patient Education
Inactivated by Surfactant
Not Used (Avoid) for Pneumonia
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3 mins
Vancomycin
Mechanism of Action
Inhibits Bacterial Cell Wall Synthesis
Indications
Serious Gram-Positive Infections
Side Effects
Nephrotoxicity
Ototoxicity
Red Man Syndrome
Thrombophlebitis
Nursing Considerations
Culture Samples First
Infuse IV Over 60 Minutes
Take Around the Clock
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2 mins
Vancomycin Side Effects & Toxicity
Side Effects
Thrombophlebitis
Nephrotoxicity
Ototoxicity
Diffuse Flushing Called Red Man Syndrome
Prevent with Antihistamine
Prevent with Slow Infusion
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2 mins
Rifampin
Tuberculosis (TB)
Blocks RNA Polymerization
Haemophilus influenzae Type B
Leprosy
Meningitis
P450 inducer
Red-orange urine
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55 secs
Clindamycin
Mechanism
Bacteriostatic
Binds 50S Ribosomal Subunit
Indications
Gram-Positive Infections
Anaerobic Infections
Side Effects
Rash
Pseudomembranous Colitis
C. Difficile (Associated Diarrhea)
Arrhythmias
Blood Dyscrasias
Considerations
Monitor for Diarrhea
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3 mins

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