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Pharmacotherapeutics for Advanced Nursing Practice, 1st. Ed., Demler & Rhoads, 2018 | Nursing (RN) School Study Aid


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Androgens, Estrogens, and Progestins
6 Picmonics to Learn | 9 mins

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Ovulatory Hormones I - Follicular Phase
0-14 Days
GnRH Stimulates FSH and LH
Follicle Secretes Estrogen
Negative Feedback from Estrogen
Increased Estrogen Leads to Positive feedback
FSH and LH Surge
Increased Estrogen from Follicle
LH Spike Leads to Ovulation
2 mins
Ovulatory Hormones II - Luteal Phase
Days 15-28
Corpus Luteum
Secretes Progesterone
Negative Feedback inhibits FSH and LH
No pregnancy forms Corpus Albicans
Stops Estrogen Secretion
Endometrial Sloughing - Menses
GnRH secretion produces new follicular phase
2 mins
Menopause Lab Findings
Decreased Estrogen
Lack of Negative Feedback
Increased FSH
Increased LH
Increased GnRH
Small Amount of Estrogen From Androgen Conversion
Increased Androgens = Hirsutism
1 min
Menopause Symptoms
Symptoms
HAVOCS Mnemonic
Hot Flashes
Atrophy of Vagina
Osteoporosis
Coronary Artery Disease (CAD)
Sleep disturbances
50 secs
Tamoxifen
Mechanism of Action
Selective Estrogen Receptor Modulator (SERM)
Antagonist on Breast Tissue
Indications
ER-positive Breast Cancer
Side Effects
Decreased Risk of Osteoporosis
Increased Risk of Endometrial Cancer
Increased Risk of Venous Thromboembolism (VTE)
1 min
Leuprolide
Mechanism
GnRH Agonist (Pulsatile Use)
GnRH Antagonist (Continuous Use)
Upregulates FSH And LH
Downregulates FSH And LH
Indications Pulsatile
Infertility
Indications Continuous
Prostate Cancer
Precocious Puberty
Uterine Fibroids
Endometriosis
Side Effects
Anti-androgenic Effects
2 mins

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