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Pharmacology and the Nursing Process, 9th Ed., Lilley, Rainforth Collins & Snyder, 2019

PART 7 - Antiinfective and Antiinflammatory Drugs

"-azole" suffix

Which prefix or suffix is best associated with antifungal medication?

Azoles (Ketoconazole)

Indications

Inhibition of Testosterone Synthesis

During your assessment of a patient taking ketoconazole which of the following is most likely to be seen?

Inhibits Ergosterol Synthesis

What mechanism of action or pharmacological action is best associated with azoles?

Inhibits P450

Liver Dysfunction

Local and Less Serious Systemic Mycosis

Which of the following is most likely an indication for treating with an azole?

Mechanism

Side Effects

Amphotericin B

Binds Ergosterol

What is the mechanism of action best associated with amphotericin B?

Forms Membrane Pores

What mechanism of action or pharmacological action is best associated with amphotericin B?

Fungal Meningitis

Which of the following diseases or disorders could most likely be treated with amphotericin B?

Last Resort for Protozoan infections

Polyene

Which of the following drug classes is associated with amphotericin B?

Systemic Mycosis

Amphotericin B Side Effects & Toxicity

Anemia

Which of the following side effects is most likely associated with amphotericin B toxicity?

Arrhythmias

Fever/Chills "Shake and Bake"

Hypotension

IV Phlebitis

Which of the following side effects is most likely a result of an acute reaction to the injection site of amphotericin B?

Milder with Liposomes

Which of the following is the most appropriate statement about the nephrotoxic symptoms associated with amphotericin B toxicity?

Nephrotoxicity

What mechanism of action or pharmacological action is best associated with Nystatin?

Candidiasis

Nystatin is most often used to treat which of the following?

Cutaneous

Nystatin is most commonly used for which of the following forms of candidiasis?

Nystatin

Oral

Rash

During your assessment of a patient with Nystatin, which of the following side effects is most likely to be seen?

Topical form of Amphotericin B

Which of the following is best associated with Nystatin?

Vaginal

42 - Antifungal Drugs

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