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Cisplatin (Platinol)

Mechanism

Alkylating Agent

Which of the following category of drugs is most likely associated with cisplatin?

Cross-Links DNA

Which of the following is the most likely mechanism of cisplatin?

Indications

Testicular Cancer

Which of the following is the most appropriate therapeutic use of cisplatin?

Ovarian Cancer

Side Effects

Nausea and Vomiting

Which of the following adverse effects is most likely associated with cisplatin?

Myelosuppression

Nephrotoxicity

Ototoxicity

Peripheral Neuropathy

Considerations

Antiemetics Before Administration

Which of the following category of medications is most appropriate to administer before treatment with cisplatin?

Aggressive Hydration

What is the most appropriate approach to avoid renal damage associated with cisplatin therapy?

Bleomycin

Which of the following is an indication for Bleomycin?

Hodgkin's Lymphoma

Mechanism of Action

Induces Free Radical Formation

What mechanism of action or pharmacological action is best associated with Bleomycin?

Breaks in DNA Strands

Pulmonary Fibrosis

Which of the following side effects is most likely associated with Bleomycin?

Skin Changes

Mucositis

WBC Differential Lab Value

White Blood Cells (WBC)

Regarding WBC lab values, which of the following is another name for "leukocytes"?

5-10 (5,000-10,000)

Regarding WBC lab values, which of the following best represents the normal range for white blood cells?

Leukocyte Differential

Neutrophils (50%-70%)

Regarding WBC lab values, which of the following best represents the normal proportion of neutrophils?

Bands  (2%-5%)

Regarding WBC lab values, which of the following best represents the normal proportion of bands?

Segs (50%-70%)

Regarding WBC lab values, which of the following best represents the normal proportion of segmented neutrophils (segs)?

Lymphocytes (20%-40%)

Regarding WBC lab values, which of the following best represents the normal proportion of lymphocytes?

Monocytes (4%-8%)

Regarding WBC lab values, which of the following best represents the normal proportion of monocytes?

Eosinophils (2%-4%)

Regarding WBC lab values, which of the following best represents the normal proportion of eosinophils?

Basophils (0.5%-1.5%)

Regarding WBC lab values, which of the following best represents the normal proportion of basophils?

46 - Antineoplastic Drugs Part 2: Cell Cycle-Nonspecific and Miscellaneous Drugs

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 - PART Chemotherapeutic Drugs and Biologic and Immune Modifiers - Lilley Pharm - 46 Antineoplastic Drugs Part 2: Cell Cycle-Nonspecific and Miscellaneous Drugs for Nursing RN

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Pharmacology and the Nursing Process, 9th Ed., Lilley, Rainforth Collins & Snyder, 2019 | Nursing (RN) School Study Aid

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