Mycobacterium Tuberculosis Characteristics
- Mycolic Acid Cell Wall
- Acid-fast
- Carbolfuchsin Stain Red
- Lowenstein-Jensen Agar
- Serpentine Cord Factor
- Primary TB
- Caseating Granuloma
- Ghon Focus
- Hilar Lymph Nodes
- Ghon Complex
- Reactivation TB
- Reactivation in Apex
Tuberculosis Assessment
- Airborne Droplet
- 3 Week Productive Cough
- Night Sweats
- Chest Pain
- Fever
- Weight Loss
- Fatigue
- Chest X-Ray
- Blood Tests
- Mantoux Skin Test
- 3 Positive Sputum Tests
Rifampin
- Tuberculosis (TB)
- Blocks RNA Polymerization
- Haemophilus influenzae Type B
- Leprosy
- Meningitis
- P450 inducer
- Red-orange urine
Tuberculosis Intervention
- Airborne Isolation
- Combination Drug Therapy (RIPE)
- 6-12 Months
- DOT
- BCG Vaccination
- Medication Education
- 3 Negative Sputum Specimens
- Infection Control
Isoniazid (INH)
- Interferes with DNA Metabolism
- Tuberculosis (TB)
- Optic Neuritis
- Nausea and Vomiting
- Hepatotoxicity
- Peripheral Neuropathy
- Vitamin B6 Prophylaxis
- Monitor AST/ALT
Ethambutol (Myambutol)
- Inhibits RNA Synthesis
- Bacteriostatic
- Tuberculosis (TB)
- Optic Neuritis
- Red/Green Color Blindness
- Gouty Arthritis
- Monitor Vision Acuity
Candida Albicans
- Fungi
- Yeast with Pseudohyphae at 20 Degrees C
- Germ Tube Formation at 37 Degrees C
- Pruritic Vaginitis
- White Cottage Cheese Discharge
- Fiery Red Mucosa
- Diabetics
- Antibiotic Use
- Esophageal Thrush in Immunocompromised
- Diaper Rash
- Endocarditis in IV Drug Users
Amphotericin B
- Systemic Mycosis
- Fungal Meningitis
- Last Resort for Protozoan infections
- Polyene
- Binds Ergosterol
- Forms Membrane Pores
Amphotericin B Side Effects & Toxicity
- Fever/Chills "Shake and Bake"
- Nephrotoxicity
- Milder with Liposomes
- Hypotension
- Anemia
- IV Phlebitis
- Arrhythmias
Azoles (Ketoconazole)
- "-azole" suffix
- Local and Less Serious Systemic Mycosis
- Inhibits Ergosterol Synthesis
- Inhibits P450
- Liver Dysfunction
- Inhibition of Testosterone Synthesis
Nystatin
- Candidiasis
- Vaginal
- Oral
- Cutaneous
- Polyene
- Binds Ergosterol
- Forms Membrane Pores
- Topical form of Amphotericin B
- Rash
Influenza Virus
- RNA Virus
- Orthomyxovirus
- Enveloped
- Negative Sense
- 8 Segments
- Helical
- Hemagglutinin for Viral Entry
- Neuraminidase for Virion Release
- Genetic Shift
- Reassortment of genome to cause major change
- Genetic Drift
- Minor Antigenic Mutations
- Reye Syndrome with Aspirin Use
- Guillain-Barre Syndrome
Influenza
- High Fever
- Cough
- Headache
- Muscle Aches
- Chills
- Vaccination
- Zanamivir (Relenza)
- Oseltamivir (Tamiflu)
Herpes Simplex Virus (HSV)
- Enveloped
- Double Stranded DNA
- Linear
- Type 1 HSV
- Gingivostomatitis
- Keratoconjunctivitis
- Encephalitis of Temporal Lobes
- Latent in Trigeminal Ganglia
- Type 2 HSV
- Genital Vesicles
- Neonatal Herpes
- TORCHES
- Latent in Sacral Ganglia
- Tzanck Test
- Multinucleated Giant Cells
- Cowdry A Inclusions
- Acyclovir
Herpes Zoster (Shingles)
- Varicella-Zoster Virus
- Linear, Unilateral Rash Along a Dermatome
- Pruritus
- Postherpetic Neuralgia
- Acyclovir
- Analgesics
- Gabapentin
- Contagious Vesicles
- Shingrix
Varicella (Chickenpox)
- Varicella Zoster Virus (VZV)
- Red Maculopapular Rash
- Vesicles Ooze and Crust
- Pruritus
- Centripetal
- Varicella Immunization
- Skin Care to Minimize Itching
- Isolate until Vesicles Crust
Acyclovir (Zovirax)
- Guanosine Analog
- Inhibits Viral Replication
- Thymidine Kinase Activation
- Herpes Simplex Virus (HSV)
- Varicella Zoster Virus (VZV)
- Headache
- GI Distress
- CNS Toxicity
- Nephrotoxicity (Crystalline Nephropathy)
- Prevents Recurrent Episodes
- Slow IV Infusion