Medical-Surgical Nursing, 10th Ed., Lewis, Dirksen, Heitkemper & Bucher | Registered Nurse (RN) School Study Aid
Cell-mediated Adaptive Immune Response
- Macrophages and Dendritic Cells Present Antigens
- T Cell Develops Antigen Specificity
- Regulatory T Cells Suppress Response
- Memory T Cells Cause Faster Secondary Response
- Cytotoxic T Cells Lyse Infected Cells
- Infected Cells Present Antigen On Surface
Cancer Warning Signs (CAUTION)
- Change in Bowel or Bladder Habits
- A Sore That Does Not Heal
- Unusual Bleeding or Discharge
- Thickening or Lump in the Breast or Elsewhere
- Dyspepsia (Indigestion)
- Obvious Change to Warts or Moles
- Nagging Cough
Busulfan
- CML
- Bone Marrow Ablation
- Cross-Links DNA
- Myelosuppression
- Pulmonary Fibrosis
- Hyperpigmentation
Cisplatin (Platinol)
- Alkylating Agent
- Cross-Links DNA
- Testicular Cancer
- Ovarian Cancer
- Nausea and Vomiting
- Myelosuppression
- Nephrotoxicity
- Ototoxicity
- Peripheral Neuropathy
- Antiemetics Before Administration
- Aggressive Hydration
Bleomycin
- Testicular Cancer
- Hodgkin's Lymphoma
- Induces Free Radical Formation
- Breaks in DNA Strands
- Pulmonary Fibrosis
- Skin Changes
- Mucositis
Vincristine (Oncovin)
- Vinca Alkaloid
- Inhibits Microtubules
- Leukemias
- Lymphomas
- Peripheral Neuropathy
- Paralytic Ileus
- Vesicant
Prednisone (Glucocorticoids)
- Glucocorticoid
- Inflammatory Conditions
- Organ Transplant Rejection
- Cataracts and Glaucoma
- Cushing's Syndrome
- Osteoporosis
- Immunosuppression
- Hyperglycemia
- Ulcers
- Adrenal Insufficiency
- Taper Gradually
Erythropoietin
- Stimulates RBC Production
- Chronic Renal Failure
- Anemia
- Increased Risk of Thrombosis
- Pelvic and Limb Pain
- Hypertension
- Do Not Shake
- Monitor Hemoglobin (Hgb) Weekly
- May Accelerate Tumor Progression
Hypercalcemia Causes
- Two CHIMPANZEES Acronym
- Thyroid Disorders
- Calcium Supplements
- Hyperparathyroidism
- Iatrogenic (Drugs, immobility)
- Milk-Alkali Syndrome
- Paget's Disease of Bone
- Acromegaly or Addison's Disease
- Neoplasms
- Zollinger-Ellison Syndrome
- Excessive Vitamin A
- Excessive Vitamin D
- Sarcoidosis
Hypercalcemia
- > 10.5 mg/dL Ca2+
- Pathologic Fractures
- Lethargy
- Hypercoagulation
- Constipation
- ECG Changes
- QT Shortening
- No Calcium Intake
- Chelating Drugs
- Calcitonin
- Bisphosphonates
- Loop Diuretics instead of Thiazide Diuretics
- Increased Risk for Renal Calculi
- Increase Fluids
Hypercalcemia Treatments
- Treat Underlying Disorder
- Hydration
- Dialysis
- Calcium Restriction
- Bisphosphonates
- Calcitonin
- Cinacalcet
- Glucocorticosteroids
- Denosumab
Cardiac Tamponade
- Fluid in the Pericardial Sac
- Pericarditis
- Decreased Cardiac Output
- Beck's Triad
- Hypotension
- Jugular Venous Distention (JVD)
- Distant Heart Sounds
- Pulsus Paradoxus
- Electrical Alternans
- Pericardiocentesis
Syndrome of Inappropriate Antidiuretic Hormone (SIADH) Nonpharmacologic Interventions
- Monitor Serum and Urine Osmolality
- IandOs with Daily Weights
- Restrict Fluid Intake
- Monitor Cardiovascular and Neurological Status
- Seizure Precautions
Syndrome of Inappropriate Antidiuretic Hormone (SIADH) Pharmacologic Interventions
- Diuretics
- Hypertonic IV Fluids
- Demeclocycline
- Tolvaptan and Conivaptan
Syndrome Of Inappropriate Antidiuretic Hormone (SIADH)
- Hypersecretion of ADH
- Increased Sensitivity to ADH
- Serum Hypoosmolality
- Coma and Seizure
- Dilutional Hyponatremia
- Cramps and Tremors
- Euvolemia
- Change in LOC
NSAIDs
- Anti-inflammatory
- Analgesic
- Fever
- Closure of Patent Ductus Arteriosus
- Reversible Inhibition of COX-1 and COX-2
- Block Prostaglandin Synthesis
- Interstitial Nephritis
- Gastric Ulcer
- Renal Ischemia
Pain Assessment
- Acute Pain
- Chronic Pain
- Onset
- Provoking or Palliative
- Quality
- Radiation
- Severity
- Timing
- Subjective Findings
- Objective Findings
- Reassessment of Pain
Ibuprofen (Advil, Motrin)
- NSAID
- COX Inhibitor
- General Pain
- Fever
- Inflammatory Conditions
- GI Ulcers
- Nephrotoxicity
- Rash
- Avoid with Alcohol
- Risk of Thrombotic Event
Morphine
- Opioid Receptor Agonist
- Pain
- Myocardial Infarction
- Nausea and Vomiting
- CNS Depression
- Biliary Colic
- Constipation
- Increased Intracranial Pressure (ICP)
- Pupillary Constriction
- Hypotension