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Tamoxifen

Mechanism of Action

Selective Estrogen Receptor Modulator (SERM)

Tamoxifen belongs to which of the following types of drugs?

Antagonist on Breast Tissue

Tamoxifen is associated with which of the following?

Indications

ER-positive Breast Cancer

Which of the following diseases or disorders is most likely an indication for tamoxifen?

Side Effects

Decreased Risk of Osteoporosis

Which of the following is associated with tamoxifen?

Increased Risk of Endometrial Cancer

What side effect is seen with use of tamoxifen?

Increased Risk of Venous Thromboembolism (VTE)

Busulfan

Which of the following is an indication for Busulfan?

Bone Marrow Ablation

Mechanism

Cross-links DNA

What mechanism of action or pharmacological action is best associated with Busulfan?

Myelosuppression

Which of the following side effects would most likely be associated with Busulfan?

Pulmonary Fibrosis

Hyperpigmentation

Cisplatin (Platinol)

Alkylating Agent

Which of the following category of drugs is most likely associated with cisplatin?

Cross-Links DNA

Which of the following is the most likely mechanism of cisplatin?

Testicular Cancer

Which of the following is the most appropriate therapeutic use of cisplatin?

Ovarian Cancer

Nausea and Vomiting

Which of the following adverse effects is most likely associated with cisplatin?

Nephrotoxicity

Ototoxicity

Peripheral Neuropathy

Considerations

Antiemetics Before Administration

Which of the following category of medications is most appropriate to administer before treatment with cisplatin?

Aggressive Hydration

What is the most appropriate approach to avoid renal damage associated with cisplatin therapy?

Vincristine (Oncovin)

Vinca Alkaloid

What mechanism of action or pharmacological action is best associated with Vincristine (Oncovin)?

Inhibits Microtubules

Leukemias

Which of the following is most likely an indication for treatment with Vincristine (Oncovin)?

Lymphomas

During your assessment of a patient taking Vincristine (Oncovin) which of the following side effects is most likely to be seen?

Paralytic Ileus

Vesicant

Which of the following medication administration or route details are best associated with Vincristine (Oncovin)?

Bleomycin

Which of the following is an indication for Bleomycin?

Hodgkin's Lymphoma

Induces Free Radical Formation

What mechanism of action or pharmacological action is best associated with Bleomycin?

Breaks in DNA Strands

Which of the following side effects is most likely associated with Bleomycin?

Skin Changes

Mucositis

Antineoplastic Medications

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