This drug is used for cognitive benefits, palliation and disease progression monitoring in Alzheimer's disease. This disease is the most common form of dementia, which is progressive and ultimately leads to death. This disease is believed to be caused by decreased acetylcholine synthesis, tau protein tangles and amyloid deposits.
This drug is an acetylcholinesterase inhibitor, which halts acetylcholine breakdown, increasing the relative amount of acetylcholine to patients.
Use of acetylcholinesterase inhibitors such as donepezil lead to increased relative amounts of acetylcholine.
Patients taking Donepezil suffer from cholinergic side effects, including nausea and dizziness.
Excess cholinergic activity can cause dizziness in patients taking Donepezil.
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