Master H2 Receptor Blocker with Picmonic for Medicine

With Picmonic, facts become pictures. We've taken what the science shows - image mnemonics work - but we've boosted the effectiveness by building and associating memorable characters, interesting audio stories, and built-in quizzing.

H2 Receptor Blocker

Block-guy blocking H (2) Tutu Receptor
Picmonic
H2 blockers are antagonists at the histamine H2 receptor, which are found within the parietal cells of the stomach. These medications can be recalled easily, because of the common suffix found in their drug names, "itidine." These drugs may help to treat GI disorders including indigestion and heartburn (GERD), and promote the healing of ulcers. This drug class exerts its action by blocking histamine H2 receptors in parietal cells of the stomach, leading to reduced acid secretion.
5 KEY FACTS
"-tidine" Suffix
Teddy

Drugs in this category have a "tidine" suffix, with examples such as cimetidine, ranitidine, famotidine and nizatidine.

INDICATIONS
Gastroesophageal Reflux Disease (GERD)
Girdle-girl

These drugs decrease parietal acid secretion to treat gastroesophageal reflux disease (GERD). GERD typically presents as regurgitation, dysphagia, heartburn when lying down, and patients may also experience night-time cough with dyspnea.

Peptic Ulcer
Pepper Ulcer-volcano

These drugs are effective against peptic ulcer disease. They promote the healing of duodenal and gastric ulcers, although recurrence is common when used alone.

MECHANISM
Block Histamine H2 Receptors
Blocking History-man in (2) Tutu Receptor

These drugs work by reversibly blocking H2 receptors as competitive inhibitors. This leads to a reduction of histamine-stimulated gastric acid secretion. Histamine is one of the primary stimulators of parietal cell acid secretion, in addition to gastrin and acetylcholine. These drugs are rapidly absorbed and effects are observed quickly.

Parietal Cells
Pirate Cell

Gastic parietal cells have a number of receptors, including the histamine H2 receptor at which these drugs are competitive inhibitors.

Unlock all 5 facts & definitions with Picmonic Free!

JOIN FREE

Take the H2 Receptor Blocker Quiz

Picmonic's rapid review multiple-choice quiz allows you to assess your knowledge.

START QUIZ NOW

It's worth every penny

Our Story Mnemonics Increase Mastery and Retention

Memorize facts with phonetic mnemonics

Unforgettable characters with concise but impactful videos (2-4 min each)

Ace Your Medical (MD/DO) Classes & Exams with Picmonic:

Over 900,000 students use Picmonic’s picture mnemonics to improve knowledge, retention, and exam performance.

Choose the #1 Medical (MD/DO) student study app.

Picmonic for Medicine (MD/DO) covers information that is relevant to your entire Medical (MD/DO) education. Whether you’re studying for your classes or getting ready to conquer the USMLE Step 1, USMLE Step 2 CK, COMLEX Level 1, or COMLEX Level 2, we’re here to help.

Works better than traditional Medical (MD/DO) flashcards.

Research shows that students who use Picmonic see a 331% improvement in memory retention and a 50% improvement in test scores.