Rhabdomyolysis is the breakdown of muscles and is a side effect of Statins.
Hepatotoxicity means toxic to the liver. This is another frequently tested side effect of Statins.
HMG CoA reductase is a rate limiting enzyme in the cholesterol synthesis pathway. Inhibition of this enzyme results in decreased cholesterol synthesis, which is the purpose of Statins.
LDL is generally recognized as the bad cholesterol because high levels of it can lead to increase risks of cardiovascular diseases. Statins decrease LDL in patients. It is important to note that they decrease LDL 3 times as much as they lower triglycerides.
Statins decreases triglyceride levels as well as LDL.
HDL is generally recognized as the good cholesterol, and Statins can actually increase HDL levels to further benefit patients.
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