Master NNRTIs (Non-nucleoside Reverse Transcriptase Inhibitors) with Picmonic for Medicine

With Picmonic, facts become pictures. We've taken what the science shows - image mnemonics work - but we've boosted the effectiveness by building and associating memorable characters, interesting audio stories, and built-in quizzing.

NNRTIs (Non-nucleoside Reverse Transcriptase Inhibitors)

Nun-Nerd-Tie
Picmonic
NNRTIs are a class of medication designed to bind to reverse transcriptase to inhibit viral DNA elongation. These medications are often combined with other therapies to treat HIV, and are different from NRTIs because they don't require intracellular metabolism. Side effects of NNRTIs are hepatotoxicity, vivid dreams and CNS effects. These medications shouldn't be used in pregnant women.
7 KEY FACTS
INDICATIONS
HIV
AIDS bandaid

These medications are used to treat HIV and AIDS.

MECHANISM
Do Not Require Intracellular Metabolism
Does Not Require Intracellular Metal-balls

These medications are different from NRTIs, as they do not require intracellular metabolism, or phosphorylation "activation" to work against HIV.

Inhibits Reverse Transcriptase
Inhibiting-chains on Reverse Train-script

These drugs work by binding to reverse transcriptase (at a different site from NRTIs), preventing viral DNA from being transcripted.

SIDE EFFECTS
Rash
Rash

Patients taking NNRTIs can often complain about developing rashes. This mainly occurs in female patients.

Hepatotoxicity
Liver with Toxic-green-glow

Hepatotoxicity is a common side effect of NNRTI drug therapy, and patients should have their liver function monitored.

Vivid Dreams and CNS Symptoms
Vivid-colors Dream from CNS-brain

Patients taking these medications have complained of vivid dreams and CNS symptoms (dizziness, confusion). The NNRTI medication efavirenz is known to cause these effects.

CONTRAINDICATION
Pregnancy
Pregnant-woman with Caution-tape

NNRTI medications, most notably delavirdine and efavirenz are contraindicated in pregnancy, and can lead to teratogenic effects.

Unlock all 7 facts & definitions with Picmonic Free!

JOIN FREE

Take the NNRTIs (Non-nucleoside Reverse Transcriptase Inhibitors) Quiz

Picmonic's rapid review multiple-choice quiz allows you to assess your knowledge.

START QUIZ NOW

It's worth every penny

Our Story Mnemonics Increase Mastery and Retention

Memorize facts with phonetic mnemonics

Unforgettable characters with concise but impactful videos (2-4 min each)

Ace Your Medical (MD/DO) Classes & Exams with Picmonic:

Over 870,000 students use Picmonic’s picture mnemonics to improve knowledge, retention, and exam performance.

Choose the #1 Medical (MD/DO) student study app.

Picmonic for Medicine (MD/DO) covers information that is relevant to your entire Medical (MD/DO) education. Whether you’re studying for your classes or getting ready to conquer the USMLE Step 1, USMLE Step 2 CK, COMLEX Level 1, or COMLEX Level 2, we’re here to help.

Works better than traditional Medical (MD/DO) flashcards.

Research shows that students who use Picmonic see a 331% improvement in memory retention and a 50% improvement in test scores.