Master Selective Alpha-1 Blockers with Picmonic for Medicine

With Picmonic, facts become pictures. We've taken what the science shows - image mnemonics work - but we've boosted the effectiveness by building and associating memorable characters, interesting audio stories, and built-in quizzing.

Selective Alpha-1 Blockers

1 only) Selective Afro (1) Wand Block-guy
Picmonic

Selective α1 blockers can be recalled by their drug names, with end with an "osin" suffix. This class of drugs exerts its action by blocking α1 adrenergic receptors in smooth muscle, arterolar and central nervous tissues. They are used to treat hypertension, while tamsulosin is specifically indicated for treatment of urinary retention in BPH.

These drugs limit the body's ability to maintain blood pressure homeostasis, and the symptoms of syncope and orthostatic hypotension are seen in patients, especially in their first dose of medication. Tamsulosin also has the side effect of priapism.

6 KEY FACTS
"-osin" suffix
Ocean

These medications can be remembered by having an "osin" suffix in their drug names: Tamsulosin, Prazosin, Terazosin, Doxazosin

MECHANISM OF ACTION
Blocks Alpha1 Receptors
Blocking the Afro (1) Wand Receptor

These medications selectively block αadrenergic receptors in smooth muscle, arteriolar and central nervous system tissues. This leads to vasodilation in arteries. Tamsulosin is selective for α1a receptors, which belong in the prostate, and is indicated for BPH while having little activity on hypertension.

INDICATIONS
Hypertension
Hiker-BP

By acting on αadrenergic receptors in arteriolar smooth muscle and causing vasodilation, these medications treat hypertension.

Benign Prostatic Hyperplasia (BPH)
Bunny Plum Hiker-plates

Tamsulosin is a drug which is selective for α1a receptors, which exist in the prostate. Thus, it is helpful in treating urinary retention in BPH, but has little effect on blood pressure.

SIDE EFFECTS
Syncope
Sink-of-peas fainting

This drug class may cause syncope, and this is especially seen with Prazosin. The body cannot adequately maintain cerebral blood pressure without α1 activity and this leads to syncope and dizziness.

Orthostatic Hypotension
Oar Hippo-BP

These medications are known for causing orthostatic hypotension, as the body poorly controls blood pressure without α1 input. Patients are cautioned to stand up slowly while on this medication.There is a "1st dose phenomenon" which occurs the first time a patient is introduced to an α1 blocker, where a sudden and severe fall in blood pressure occurs with body position changes.Tamsulosin has been linked to priapism.

Unlock all 6 facts & definitions with Picmonic Free!

JOIN FREE

Take the Selective Alpha-1 Blockers Quiz

Picmonic's rapid review multiple-choice quiz allows you to assess your knowledge.

START QUIZ NOW

It's worth every penny

Our Story Mnemonics Increase Mastery and Retention

Memorize facts with phonetic mnemonics

Unforgettable characters with concise but impactful videos (2-4 min each)

Ace Your Medical (MD/DO) Classes & Exams with Picmonic:

Over 870,000 students use Picmonic’s picture mnemonics to improve knowledge, retention, and exam performance.

Choose the #1 Medical (MD/DO) student study app.

Picmonic for Medicine (MD/DO) covers information that is relevant to your entire Medical (MD/DO) education. Whether you’re studying for your classes or getting ready to conquer the USMLE Step 1, USMLE Step 2 CK, COMLEX Level 1, or COMLEX Level 2, we’re here to help.

Works better than traditional Medical (MD/DO) flashcards.

Research shows that students who use Picmonic see a 331% improvement in memory retention and a 50% improvement in test scores.