Yolk-sac tumor is a germ-cell tumor, also known as endodermal sinus tumor. It is the most common germ cell tumor found in infants, but is rare overall.
AFP, or alpha-fetoprotein is the tumor marker used to detect yolk sac tumors.
This type of ovarian tumor shows aggressive malignancy in the ovaries and sacrococcygeal area of younger children.
Yolk sac tumors often present with a yellow non-encapsulated mucinous mass. This is described as friable and solid.
Schiller-Duval bodies are glomerulus-like structures and are present in 50% of cases of yolk sac tumors. If found, these structures are pathognomonic for yolk sac tumors.
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