α-synuclein is the main component of eosinophilic cytoplasmic inclusions, which are found in Lewy bodies. These are identified histologically in brain tissue.
Lewy bodies are eosinophilic cytoplasmic inclusions within nerve cells.
Histologically, Lewy bodies are characteristic of Parkinson's disease, and are found in post-mortem examination.
Lewy body dementia is also associated with Lewy bodies. This disorder is described as an initial dementia with visual hallucinations, which is followed by parkinsonian features.
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