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Anti-glomerular Basement Membrane Antibodies

Anti-glow-mare Ant-tie-body inside Basement Membrane
Picmonic
Anti-glomerular basement membrane antibodies are IgG and IgM antibodies directed against protein in the basements membranes of kidney glomeruli and lung alveoli. This results in the clinical condition Goodpasture's disease which is characterized by glomerulonephritis resulting in hematuria and lung damage resulting in hemoptysis.
5 KEY FACTS
Glomerulonephritis
Glow-mare

The formation of anti-glomerular basement membrane antibodies results in glomerulonephritis due to damage to the kidney glomerular basement membrane.

Goodpasture's Disease
Gold-pastor

This is the name of the disease entity resulting from the formation of anti-glomerular basement membrane antibodies. It is characterized by lung and kidney damage.

Linear immunofluorescence
Linear In-moon-fluorescence

A kidney biopsy demonstrating linear IgG deposits along the basement membrane of the kidney glomerulus is diagnostic of Goodpasture’s disease.

Hemoptysis
Red-mop coughing blood

Damage to the basement membranes of lung alveoli results in the patient coughing up blood.

Hematuria
Red-urinal

Damage to the basement membranes of kidney glomeruli results in the patient peeing blood.

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