Master Rabies Virus with Picmonic for Medicine

With Picmonic, facts become pictures. We've taken what the science shows - image mnemonics work - but we've boosted the effectiveness by building and associating memorable characters, interesting audio stories, and built-in quizzing.

Rabies Virus

Rabid rabbit virus
Picmonic
Rabies virus is an enveloped negative sense single stranded RNA virus that causes fatal rabies disease in humans and animals. The virus has helical symmetry has a characteristic bullet shaped viral capsid. This virus is transmitted when a human or animal is injected with infected saliva, usually during a bite. The virus binds to acetylcholine receptors in cells and replicates at the site of inoculation. The virus then travels quickly along the peripheral nervous system via retrograde axonal transport to the CNS. From the CNS, the virus spreads to other organs including the salivary glands. These tissues in the mouth and cheeks receive high concentrations of the virus allowing it to be further transmitted in saliva. Neurons infected by the rabies virus can be identified via visualization of Negri bodies, which are eosinophilic inclusion bodies found in the cytoplasm of neurons that represent ribonuclear proteins produced by the virus. The Negri bodies are often found in purkinje cells of the cerebellum and can be used as definite histological proof of rabies infection. 
11 KEY FACTS
CHARACTERISTICS
Enveloped
Envelope

This virus has an envelope covering its protein capsid.

RNA Virus
RNA-rhino

Rabies virus has an RNA genome.

SS Negative Linear
SS Negative (-)

Negative-sense 3 to 5 viral RNA genome is complementary to viral mRNA. Therefore, the genome must be converted to positive-sense RNA by an RNA polymerase before translation can occur. Viruses with negative-sense genomes must carry an RNA polymerase inside the virion in order to replicate.

Helical
Helical-shape

Rabies virus has helical symmetry with infectious particles that have cylindrical shape.

Bullet-Shaped Capsid
Bullet

The rabies virus has a characteristic bullet-shaped protein capsid.

Binds to Acetylcholine Receptor
A-seagull-cola receptor

Rabies virus attaches to acetylcholine receptors of cells.

Retrograde Fashion
Backwards bullet

Retrograde transport is the movement of molecules or organelles away from the synapse of a neuron toward the cell body and is mediated by dynein. The rabies virus travels quickly along the peripheral nervous system via retrograde axonal transport to the CNS.

Migrates to Saliva
Saliva

From the CNS, the rabies virus travels to other organs including the salivary glands. These tissues in the mouth and cheeks receive high concentrations of the virus allowing it to be further transmitted in saliva. Therefore, rabies virus is normally transmitted via a bite from an infected host.

DIAGNOSIS
Negri Bodies
Nigerian

Neurons infected by the rabies virus can be identified via visualization of Negri bodies, which are eosinophilic inclusion bodies found in the cytoplasm of neurons that represent ribonuclear proteins produced by the virus.

Cytoplasmic Inclusions in Neurons
Ink-blot

Neurons infected by the rabies virus can be identified via visualization of Negri bodies, which are eosinophilic inclusion bodies found in the cytoplasm of neurons that represent ribonuclear proteins produced by the virus.

Purkinje Cells of Cerebellum
Purple pinky Silver-cerebellum-bell

Negri bodies are often found in purkinje cells of the cerebellum and can be used as definite histological proof of rabies infection.

Unlock all 11 facts & definitions with Picmonic Free!

JOIN FREE

Take the Rabies Virus Quiz

Picmonic's rapid review multiple-choice quiz allows you to assess your knowledge.

START QUIZ NOW

It's worth every penny

Our Story Mnemonics Increase Mastery and Retention

Memorize facts with phonetic mnemonics

Unforgettable characters with concise but impactful videos (2-4 min each)

Ace Your Medical (MD/DO) Classes & Exams with Picmonic:

Over 870,000 students use Picmonic’s picture mnemonics to improve knowledge, retention, and exam performance.

Choose the #1 Medical (MD/DO) student study app.

Picmonic for Medicine (MD/DO) covers information that is relevant to your entire Medical (MD/DO) education. Whether you’re studying for your classes or getting ready to conquer the USMLE Step 1, USMLE Step 2 CK, COMLEX Level 1, or COMLEX Level 2, we’re here to help.

Works better than traditional Medical (MD/DO) flashcards.

Research shows that students who use Picmonic see a 331% improvement in memory retention and a 50% improvement in test scores.