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Coxiella burnetii

Cock with brunette wig
Picmonic
Coxiella burnetii is a small gram-negative bacterium. It is not in the Rickettsial genus, but is closely related and is an obligate intracellular organism that requires CoA and NAD for survival. However, unlike the other Rickettsial infections, Coxiella is not transmitted by an arthropod vector, does not cause a rash, and has a negative Weil-Felix reaction. Instead, Coxiella burnetii is commonly acquired via inhalation of spores from cattle placenta and is the cause of Q fever. Symptoms include pneumonia and flu like symptoms. Treatment with tetracycline or doxycycline can reduce the symptomatic duration of illness. 
8 KEY FACTS
Gram-Negative Bacteria
Graham-cracker Negative-devil with Bacteria

Coxiella burnetii is a small gram-negative bacterium. It is not in the Rickettsial genus, but is closely related and is an obligate intracellular organism that requires CoA and NAD for survival. However, unlike the other Rickettsial infections, Coxiella is not transmitted by an arthropod vector, does not cause a rash, and has a negative Weil-Felix reaction.

No Arthropod Vector
Negative Anti-tick/insect Vector

Unlike the other Rickettsial infections, Coxiella does not have an arthropod vector through which it is transmitted.

No Rash
Negative Rash

Unlike the other Rickettsial infections, Coxiella does not cause a rash.

Negative Weil-Felix
Negative Whale

A Weil-Felix reaction is seen in patients with Rickettsial infections other than Coxiella. When patient serum with Rickettsial antibodies is mixed with Proteus antigens, the antiricketssial antibodies cross-react to Proteus O antigens and cause agglutination. Unlike the other Rickettsial infections, Coxiella causes a negative Weil-Felix reaction.

Cattle Placenta
Cattle Placenta

This organism is common in cattle, sheep, and goats and can be acquired via inhalation of spores from contaminated birthing products like cattle placenta. Due to this mode of transmissions, at risk occupations include veterinary personnel, farmers, and shearers.

Q Fever
(Q) Queen Fever-beaver

Q fever is the disease caused by Coxiella burnetii and commonly manifests as flu-like symptoms with fever, malaise, myalgia, nausea, vomiting, and diarrhea. During the course of disease, it can progress to a pneumonia, which can result in life-threatening acute respiratory distress syndrome.

Pneumonia
Nude-Mona

Q fever is the disease caused by Coxiella burnetii and commonly manifests as flu-like symptoms with fever, malaise, myalgia, nausea, vomiting, and diarrhea. During the course of disease, it can progress to a pneumonia, which can result in life-threatening acute respiratory distress syndrome.

Flu-like Symptoms
Thermometer and Ice-bag

Q fever is the disease caused by Coxiella burnetii and commonly manifests as flu-like symptoms with fever, malaise, myalgia, nausea, vomiting, and diarrhea. During the course of disease, it can progress to a pneumonia, which can result in life-threatening acute respiratory distress syndrome.

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