Master Polyomavirus with Picmonic for Medicine

With Picmonic, facts become pictures. We've taken what the science shows - image mnemonics work - but we've boosted the effectiveness by building and associating memorable characters, interesting audio stories, and built-in quizzing.

Polyomavirus

Polly-o-virus
Picmonic

Polyomaviruses are non-enveloped, double-stranded, circular DNA viruses that can cause progressive multifocal leukoencephalopathy (JC virus) and nephropathy (BK virus). BK virus is a member of the Polyomavirus family which rarely causes disease. This is because infected individuals are typically asymptomatic. The virus can disseminate to the kidneys and urinary tract, where it persists in the latent form until some form of immunosuppression develops. Typically, this occurs in the setting of kidney or multi-organ transplantation. Clinical manifestations include renal dysfunction with a progressive rise in serum creatinine on lab evaluation, along with renal tubular cells and inflammatory cells on urinalysis. JC virus is also a type of Polyomavirus that causes progressive multifocal leukoencephalopathy (PML) in the immunocompromised, such as HIV patients. Progressive multifocal leukoencephalopathy is a rare disease characterized by inflammation of the white matter of the brain in multiple locations. Specifically, this virus destroys oligodendrocytes that are responsible for creating the myelin sheath in the CNS. Destruction of these oligodendrocytes leads to demyelination, which impairs the transmission of nerve impulses.

10 KEY FACTS
CHARACTERISTICS
Non-enveloped
Nun-envelope

While some viruses have viral envelopes covering their protein capsids, polyomaviruses do not.

Double stranded DNA
DNA Double-helix

Polyomavirus genomes consist of double-stranded DNA, meaning their genetic code consists of deoxyribonucleic acid, as opposed to ribonucleic acid.

Circular
Circular-object

This genome is circular, as opposed to linear.

DISEASE
BK virus
BK Drive Through

BK virus is a member of the Polyomavirus family, and is known to cause renal dysfunction in the immunosuppressed.

Kidney damage
Kidney with Damage

BK virus can disseminate to the kidneys and urinary tract, where it persists in its latent form until some form of immunosuppression develops. Typically, this occurs in the setting of kidney or multi-organ transplantation. Clinical manifestations include renal dysfunction with a progressive rise in serum creatinine on lab evaluation, along with renal tubular cells and inflammatory cells on urinalysis.

JC virus
JC-on-a-penny

JC virus is another member of the Polyomavirus family which causes progressive multifocal leukoencephalopathy (PML) in the immunocompromised, including HIV patients.

Progressive Multifocal Leukoencephalopathy (PML)
PML-license-plate

Progressive multifocal leukoencephalopathy (PML) is a rare disease characterized by inflammation of the white matter of the brain in multiple locations. Specifically, this virus destroys oligodendrocytes that are responsible for creating the myelin sheath in the CNS.

HIV/AIDS
Band-AIDS

Progressive multifocal leukoencephalopathy (PML) is seen almost exclusively in immunosuppressed patients, such as those with HIV.

Oligodendrocyte
Old goalie

JC virus destroys oligodendrocytes that are responsible for creating the myelin sheath in the CNS. Destruction of the oligodendrocytes leads to demyelination, which impairs the transmission of nerve impulses.

Demyelination of CNS
Unraveling-myelin on neuron

This virus specifically destroys oligodendrocytes that are responsible for creating the myelin sheath in the CNS. Destruction of the oligodendrocytes leads to demyelination, which impairs the transmission of nerve impulses.

Unlock all 10 facts & definitions with Picmonic Free!

JOIN FREE

Take the Polyomavirus Quiz

Picmonic's rapid review multiple-choice quiz allows you to assess your knowledge.

START QUIZ NOW

It's worth every penny

Our Story Mnemonics Increase Mastery and Retention

Memorize facts with phonetic mnemonics

Unforgettable characters with concise but impactful videos (2-4 min each)

Ace Your Medical (MD/DO) Classes & Exams with Picmonic:

Over 870,000 students use Picmonic’s picture mnemonics to improve knowledge, retention, and exam performance.

Choose the #1 Medical (MD/DO) student study app.

Picmonic for Medicine (MD/DO) covers information that is relevant to your entire Medical (MD/DO) education. Whether you’re studying for your classes or getting ready to conquer the USMLE Step 1, USMLE Step 2 CK, COMLEX Level 1, or COMLEX Level 2, we’re here to help.

Works better than traditional Medical (MD/DO) flashcards.

Research shows that students who use Picmonic see a 331% improvement in memory retention and a 50% improvement in test scores.