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Diphyllobothrium Latum

Dolphin-bottom L
Picmonic
Diphyllobothrium latum is a parasitic infection classified as a tapeworm, or cestode. It occurs through the ingestion of larvae from raw freshwater fish, and leads to macrocytic anemia in patients. This occurs because this tapeworm competes for B12 with the host in the intestines. The preferred treatment for diphyllobothrium latum infection is praziquantel.
5 KEY FACTS
PATHOPHYSIOLOGY
Cestode (Tapeworm)
Crest-toad with Tapeworm

Diphyllobothrium latum is a cestode, or tapeworm.

Ingestion of Larvae from Raw Fish
Raw Fish

Patients become infected with diphyllobothrium after ingesting larvae from raw fish.

Competes for Vitamin B12
Competing with (12) Dozen Viking (B) Bees

Roughly 80% of patients infected are asymptomatic and can go for years without having their infection detected. The parasite then absorbs up to 80% or more of the host's B12 intake, which leads to megaloblastic anemia.

Megaloblastic Anemia
Mega-blast Anemone

The B12 deficiency in patients can lead to a megaloblastic anemia, which is indistinguishable from pernicious anemia. This megaloblastic anema can also translate into subtle demyelinative neurological symptoms.

TREATMENT
Praziquantel
Pretzel-queen

The standard treatment for this infection is praziquantel, but it should be noted that this is treatment regimen is not FDA approved.

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