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Focal Segmental Glomerulosclerosis

Most Common Cause of Nephrotic Syndrome in Hispanics and African Americans

Which of the following is most likely associated with Focal Segmental Glomerulosclerosis?

Associated with Sickle Cell Disease and HIV

Which of the following is the most likely associated with acquiring Focal Segmental Glomerulosclerosis?

LM Segmental Sclerosis and Hyalinosis

Which microscopic finding or histological description is associated with Focal Segmental Glomerulosclerosis?

EM Focal Damage of Visceral Epithelial Cells

IF Negative

Microscopic Hematuria

During your assessment of a patient with Focal Segmental Glomerulosclerosis which of the following is most likely to be seen?

Nonselective Proteinuria

Poor Prognosis

Associated Interferon Therapy and Heroin Abuse

Which of the following is most likely true of focal segmental glomerulosclerosis?

Histopathology

Signs & Symptoms

Considerations

Membranous Glomerulonephritis

Nephrotic

Which of the following best describes membranous glomerulonephritis?

LM Thickening of Capillary and Glomerular Basement Membrane (GBM)

Which of the following microscopic findings is most likely associated with membranous glomerulonephritis?

EM Spike and Dome Appearance with Subepithelial Deposits

IF Granular

Gold

Which of the following medications is most likely associated with membranous glomerulonephritis?

Solid Tumors

Which of the following is a secondary cause of membranous glomerulonephritis?

Hepatitis B Virus (HBV)

Lupus

Characteristics

Diagnosis

Secondary

Primary

Phospholipase A2 Receptor Autoantibodies

Which of the following is most likely associated with primary membranous glomerulonephritis?

NSAIDS

Membranoproliferative Glomerulonephritis

Nephritic-Nephrotic Syndrome

Which of the following best classifies membranoproliferative glomerulonephritis?

Type I

Which type of membranoproliferative glomerulonephritis is characterized by subendothelial IgG deposits on the glomerular basement membrane?

Subendothelial Immune Complexes

Which of the following microscopic findings is most likely associated with type I membranoproliferative glomerulonephritis?

Hepatitis C Virus

Which of the following infections is most likely associated with type I membranoproliferative glomerulonephritis?

Granular IF

Which of the following immunofluorescence patterns is most likely seen in type I membranoproliferative glomerulonephritis?

Tram Tracks Caused by Splitting of the GBM

Ingrowth of Mesangium

Type II

Which type of membranoproliferative glomerulonephritis is characterized by persistent complement activation and C3 deposiits on the glomerular basement membrane?

Dense Deposit Disease

Which of the following is synonymous with type II membranoproliferative glomerulonephritis?

C3 Nephritic Factor

Which of the following autoantibodies is most likely present in patients with type II membranoproliferative glomerulonephritis?

Diabetic Glomerulonephropathy

Nonenzymatic Glycosylation of Glomerular Basement Membrane

Which of the following is most likely associated with the pathophysiology of Diabetic Glomerulonephropathy?

Nonenzymatic Glycosylation of Arterioles

Hyaline Arteriolosclerosis

Which of the following histological findings is most likely associated with Diabetic Glomerulonephropathy?

Increased GFR

Which of the following is most likely associated with the pathophysiology of early-stage Diabetic Glomerulonephropathy?

Mesangial Expansion

Type IV Collagen Deposition

Kimmelstiel Wilson Lesions

Diabetic Glomerulonephropathy is most likely classified as which of the following?

Pathophysiology

Histological Findings

Presentation

Hyperfiltration

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