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First Aid
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First Aid for the USMLE Step 2 CK (10th Ed.)
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Substance Use Disorders

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First Aid for the USMLE Step 2 CK (10th Ed.) | Medicine (MD/DO) School Study Aid

Substance Use Disorders
30 Picmonics to Learn | 51 mins
Long-acting Benzodiazepines
Drug Names
Lorazepam
Diazepam
Clonazepam
Chlordiazepoxide
Indications
Insomnia
Anxiety
Seizures
Eclampsia
Alcohol Withdrawal
Considerations
Half-life > 24 Hours
Dependence
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3 mins
Substance Use Disorder
Diagnostic Criteria
2 or More Symptoms For 1 year
Tolerance
Withdrawal Symptoms
Cravings
Using More Than Intended
Inability to Cut Down
Time-Consuming Substance Acquisition
Impaired Functioning at Work
Reduced Recreational Activities
Dangerous Activities
Continued Use
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2 mins
Substance Use Disorder Assessment (Formerly Substance Abuse Assessment)
Changes in Mood
Poor Hygiene
Odd Sleep Patterns
Frequent Injuries
Relationship or Job Difficulty
Poor Performance
Anorexia OR Weight Loss
Social Isolation
Financial Problems
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2 mins
Opioid Use Disorder and Withdrawal Assessment (Formerly Opioid Abuse and Withdrawal Assessment)
Abuse Assessment
Euphoria
Miosis
CNS Depression
Abuse Withdrawal
Yawning
Gooseflesh
Sweating
Rhinorrhea
Kicking Movements
Consideration
Naloxone
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1 min
Opioids Overview
Indications
Pain
Weaning
Cough
Diarrhea
Mechanism of Action
Agonists at Mu (μ), Kappa (Κ), and Delta (δ) Receptors
Decrease Synaptic Transmission
Side Effects
Respiratory Depression
Addiction
Miosis
Constipation
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2 mins
Opioid Antidote
Antidote
Naloxone
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29 secs
Naloxone (Narcan)
Mechanism
Competitive Opioid Receptor Antagonist
Indications
Opioid Induced CNS Depression
Side Effects
Severe Nausea and Vomiting
Excitable State
Opioid Withdrawal Symptoms
Considerations
Repeated Dosing Often Required
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1 min
Buprenorphine-Naloxone (Suboxone)
Mechanism of Action
Combination Drug
Partial Opioid Receptor Agonist (Buprenorphine)
Opioid Receptor Antagonist (Naloxone)
Indication
Opioid Use Disorder
Side Effects
CNS Depression
Diaphoresis
Hypotension
Considerations
Low Abuse Potential
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2 mins
Codeine
Mechanism
Opioid Receptor Agonist
Indications
Mild to Moderate Pain
Cough Suppressant
Side Effects
Sedation
Constipation
Miosis
Considerations
Close Monitoring When Breast Feeding
Often Combined with Non-Opioids
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2 mins
Tramadol
Indications
Chronic Pain
Mechanism of Action
Weak Opioid
Inhibit Serotonin and NE reuptake
Side Effect
Increased Risk of Seizure
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48 secs
Oxycodone
Mechanism of Action
Opioid Receptor Agonist
Indication
Refractory Pain
Side Effects
Respiratory Depression
Constipation
CNS Depression
Considerations
Addiction
Naloxone
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2 mins
Morphine
Mechanism
Opioid Receptor Agonist
Indications
Pain
Myocardial Infarction
Side Effects
Nausea and Vomiting
CNS Depression
Biliary Colic
Constipation
Increased Intracranial Pressure (ICP)
Pupillary Constriction
Hypotension
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2 mins
Fentanyl
Mechanism of Action
Opioid Receptor Agonist
High Potency
Indications
Anesthesia Induction
Chronic Pain
Breakthrough Pain
Side Effects
CNS Depression
Respiratory Depression
Constipation
Miosis
Considerations
Addiction
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3 mins
Alcohol Use Disorder Assessment (Formerly Alcohol Abuse Assessment)
Intoxication
CNS Depression
Withdrawal
Wernicke-Korsakoff Syndrome
Medical Complications
GI Distress
Cardiomyopathy
Pancreatitis
Cirrhosis
Immunosuppression
Sexual Dysfunction
Considerations
Screening (Assessments)
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3 mins
Wernicke-Korsakoff Syndrome
Thiamine deficiency
Confusion
Ophthalmoplegia
Ataxia
Korsakoff
Confabulation
Personality Changes
Memory loss
Alcoholics
Damage to medial dorsal nucleus
Damage to mammillary bodies
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2 mins
Alcohol Use Disorder Interventions (Formerly Alcohol Abuse Interventions)
Withdrawal
Reduce Environmental Stimuli
Antianxiety Medications
Vitamin Supplements
Seizure Precautions
Suicide Precautions
Fever
Considerations
Identify Support Systems
Group Therapy
Disulfiram
Naltrexone
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2 mins
Amphetamines Intoxication Assessment
Euphoria
Insomnia
Mydriasis
Diaphoresis
Hypertension
Tachycardia
Paranoia
Anxiety
Anorexia
Seizures
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2 mins
Amphetamine Antidote
Antidote
Ammonium Chloride (NH4Cl)
Acidify Urine
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34 secs
Cocaine Intoxication Assessment
Euphoria
Delusions
Mydriasis
Hallucinations
Agitation
Hypertension
Arrhythmias
Hyperthermia
Seizures
Nasal Septum Perforation
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2 mins
Phencyclidine (PCP) Intoxication Assessment
Violent Behavior
Motor Issues
Nystagmus
Increased Pain Tolerance
Tachycardia
Delirium
Psychosis
Seizures
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2 mins
LSD Intoxication Assessment
Psychosis
Perceptual Distortion
Visual Hallucinations
Paranoia
Depersonalization
Anxiety
Tachycardia
Flashbacks
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2 mins
Marijuana Intoxication Assessment
Euphoria
Slowed Reaction Time
Conjunctival Injection
Increased Appetite
Anxiety
Social Withdrawal
Paranoid Delusions
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2 mins
Barbiturates
Barb- Drug Names
Indications
Seizure Treatment
Anesthesia Induction
Mechanism of Action
Increased Duration of Cl- Channel Opening
Decrease Neuron Firing
Side Effects
Sedation
Cardiovascular and Respiratory Depression
CNS Depression
P450 inducer
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2 mins
Phenobarbital (Barbiturates)
Mechanism
Barbiturate
Indications
Seizures
Side Effects
Ataxia
Paradoxical Excitement
Fatigue/Drowsiness
Considerations
Monitor Plasma Levels
High Potential for Abuse
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1 min
Benzodiazepine Intoxication Assessment
Drowsiness
Confusion
Respiratory Depression
Hypotension
Coma
Treatment
Flumazenil (Romazicon)
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2 mins
Benzodiazepines Overview
Indications
First Line for Status Epilepticus
Anesthesia Induction
Anxiety
Eclampsia
Detoxification
Mechanism of Action
'-zepam' and '-zolam" Suffix
Increase Frequency of Cl- Channel Opening
Side Effects
Decrease REM Sleep
CNS Depression
Dependence
Antidote
Flumazenil for Overdose
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2 mins
Short-acting Benzodiazepines
Mnemonic
ATOM
Drug Names
Alprazolam
Triazolam
Oxazepam
Midazolam
Indications
Anesthesia Induction
Insomnia
Anxiety
Considerations
Half-life < 12 Hours
Dependence
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2 mins
CNS Stimulants
Indications
Attention Deficit Hyperactivity Disorder (ADHD)
Obesity
Mechanism of Action
Increase Catecholamines at Synaptic Cleft
Increase Norepinephrine
Increase Dopamine
Drug Names
Methylphenidate (Ritalin)
Methamphetamine
Side Effect
Potential for Abuse
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57 secs
CNS Stimulant Indications
Drug Names
Amphetamine
Methylphenidate (Ritalin)
Mechanism of Action
Increased Norepinephrine
Increased Dopamine
Indications
Attention Deficit Hyperactivity Disorder (ADHD)
Obesity
Narcolepsy
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1 min
CNS Stimulant Side Effects
Side Effects
Agitation
Insomnia
Hypertension
Tachycardia
Tics
Anorexia
Considerations
Tolerance Develops
High Risk of Abuse and Dependence
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2 mins

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