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USMLE Step 2

Berger's Disease (IgA Nephropathy)

Nephritic

Which of the following characteristics describes the pathogenesis of Berger's disease (IgA nephropathy)?

IgA Nephropathy

Which of the following nephropathies best describes Berger's disease?

Immune Complex Deposit in Mesangium

Which of the following microscopic findings is most likely associated with Berger's disease (IgA nephropathy)?

Increased Synthesis of IgA

Which of the following findings is most likely seen in patients with Berger's disease (IgA nephropathy)?

Most Common Cause of Nephritic Syndrome

Which of the following statements is most  likely associated with Berger's disease (IgA nephropathy)?

Overlapping Features with Henoch–Schönlein Purpura

Presents with Pharyngitis, URI or Acute Gastroenteritis

Which of the following clinical findings is most likely associated with Berger's disease (IgA nephropathy)?

Loop of Henle

Descending Limb

In the loop of Henle, which of the following is most likely the site where filtrate travels from renal cortex to renal medulla?

Water Follows Na+

Which of the following characteristics is most likely associated with the descending limb of the loop of Henle?

Medullary Hypertonicity

Which of the following characteristics facilitates the reabsorption of water in the descending limb of the loop of Henle?

Increased Water Reabsorption

Vasa Recta

Which part of the loop of Henle is made up of a series of capillaries that actively transport sodium?

Na+ Reabsorbed Via Active Transport

Which of the following processes occurs between the ascending limb of the loop of Henle and the vasa recta?

Ascending Limb

In the loop of Henle, which of the following is most likely the site of active solute reabsorption?

Decreased Concentration of Filtrate

Which of the following characteristics is most likely associated with the ascending limb of the loop of Henle?

Distal Tubule

After the loop of Henle, which part of the nephron does filtrate traverse next?

Characteristics

Reabsorbs Na+, K+, Cl-

Impermeable to Water

Post Streptococcal Glomerulonephritis

Which of the following characteristics is best associated with poststreptococcal glomerulonephritis?

Follows Group A Streptococcal pharyngitis or Skin Infection

Which of the following is most commonly associated with poststreptococcal glomerulonephritis?

Neutrophils

Infiltration of the glomeruli with which of the following cell-types is best associated with poststreptococcal glomerulonephritis?

Immunofluorescence (IF) Granular

Which microscopic finding or histological description is most commonly associated with poststreptococcal glomerulonephritis?

Subepithelial Immune Complex Humps

Lumpy Bumpy Appearance on Immunofluorescence (IF)

Children

Which of the following groups of people are most commonly associated with poststreptococcal glomerulonephritis?

Edema

Which of the following signs, symptoms, or diseases is most commonly seen in patients with poststreptococcal glomerulonephritis?

Cola Colored Urine

Pathophysiology

Signs and Symptoms

Diagnosis

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